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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3759944
Molecular formula	C25H39ClN4O4
IUPAC name	4-amino-5-chloro-N-[(3R,4S)-1-[[1-(2,2-dimethylpropanoyl)piperidin-4-yl]methyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide
Molecular weight	495.061
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.9
Synonyms	FNMBJONFSYMEGN-RBBKRZOGSA-N SCHEMBL3316704 BDBM50142920 cis-4-amino-5-chloro-N-[1-((1-pivaloylpiperidin-4-yl)methyl)-3-methoxypiperidin-4-yl]-2-methoxybenzamide
Inchi Key	FNMBJONFSYMEGN-RBBKRZOGSA-N
Inchi ID	InChI=1S/C25H39ClN4O4/c1-25(2,3)24(32)30-10-6-16(7-11-30)14-29-9-8-20(22(15-29)34-5)28-23(31)17-12-18(26)19(27)13-21(17)33-4/h12-13,16,20,22H,6-11,14-15,27H2,1-5H3,(H,28,31)/t20-,22+/m0/s1
PubChem CID	68592173
ChEMBL	CHEMBL3759944
IUPHAR	N/A
BindingDB	50142920
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
523950	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
523951	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388

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