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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL201946
Molecular formula	C17H20N2O2
IUPAC name	[(1R,8S)-2,3,5,6,7,8-hexahydro-1H-pyrrolizin-1-yl]methyl 1H-indole-3-carboxylate
Molecular weight	284.359
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.7
Synonyms	BDBM50181840 (1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Methyl-1Hindole-3-carboxylate
Inchi Key	FQUPQQRFDMPEMK-LRDDRELGSA-N
Inchi ID	InChI=1S/C17H20N2O2/c20-17(14-10-18-15-5-2-1-4-13(14)15)21-11-12-7-9-19-8-3-6-16(12)19/h1-2,4-5,10,12,16,18H,3,6-9,11H2/t12-,16-/m0/s1
PubChem CID	44407083
ChEMBL	CHEMBL201946
IUPHAR	N/A
BindingDB	50181840
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
85081	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
85084	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
85085	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
85082	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
85083	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
85080	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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