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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL37333
Molecular formula	C16H22ClN3O2
IUPAC name	4-amino-5-chloro-N-[[(1R,8R)-2,3,5,6,7,8-hexahydro-1H-pyrrolizin-1-yl]methyl]-2-methoxybenzamide
Molecular weight	323.821
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.1
Synonyms	(exo) 4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-ylmethyl)-2-methoxy-benzamide 4-Amino-5-chloro-2-methoxy-N-[[[(7abeta)-hexahydro-1H-pyrrolizin]-1beta-yl]methyl]benzamide BDBM50005841 4-amino-5-chloro-N-[(1R,7aR)-hexahydro-1H-pyrrolizin-1-ylmethyl]-2-methoxybenzamide
Inchi Key	GAYSOZKZPOVDSB-QMTHXVAHSA-N
Inchi ID	InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-9-10-4-6-20-5-2-3-14(10)20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21)/t10-,14-/m1/s1
PubChem CID	15095973
ChEMBL	CHEMBL37333
IUPHAR	N/A
BindingDB	50005841
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
92054	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
92055	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
92056	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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