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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BIMU-8
Molecular formula	C19H26N4O2
IUPAC name	N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-3-propan-2-ylbenzimidazole-1-carboxamide
Molecular weight	342.443
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.5
Synonyms	AC1NSJV2 ZINC252666018 GTPL234 SCHEMBL8947433 BDBM84648 N-[(1alpha,5alpha)-8-Methyl-8-azabicyclo[3.2.1]octan-3beta-yl]-2,3-dihydro-2-oxo-3-isopropyl-1H-benzimidazole-1-carboxamide ZINC101208813 N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-3-propan-2-ylbenzimidazole-1-carboxamide [ Show all ]
Inchi Key	AFOFVIBWSLOHFR-GOOCMWNKSA-N
Inchi ID	InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24)/t13?,14-,15+
PubChem CID	5311029
ChEMBL	N/A
IUPHAR	234
BindingDB	84648
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553262	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
553263	5-hydroxytryptamine receptor 4	P97288	Htr4	Mus musculus (Mouse)	388
553264	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
555497	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
555496	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448

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