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Name | 5-hydroxytryptamine receptor 4 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Htr4 |
Synonym | 5-HT-4 5-HT4 5-HT4 receptor 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled serotonin receptor 4 |
Disease | N/A for non-human GPCRs |
Length | 388 |
Amino acid sequence | MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT |
UniProt | P97288 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2183 |
IUPHAR | 9 |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
553263 | BIMU-8 | C19H26N4O2 | 342.443 | 3 / 1 | 2.5 | Yes |
6911 | CHEMBL324057 | C20H28N4O2 | 356.47 | 3 / 1 | 2.9 | Yes |
555521 | tryptamine | C10H12N2 | 160.22 | 1 / 2 | 1.6 | Yes |
555613 | Clebopride | C20H24ClN3O2 | 373.881 | 4 / 2 | 3.2 | Yes |
553518 | cisapride | C23H29ClFN3O4 | 465.95 | 7 / 2 | 3.4 | Yes |
553651 | Zacopride | C15H20ClN3O2 | 309.794 | 4 / 2 | 1.7 | Yes |
553655 | SDZ-205557 | C14H21ClN2O3 | 300.783 | 5 / 1 | 3.2 | Yes |
90900 | CHEMBL470432 | C19H25N3OS | 343.489 | 4 / 0 | 5.2 | No |
553714 | SC-53116 | C16H22ClN3O2 | 323.821 | 4 / 2 | 2.1 | Yes |
553794 | Renzapride | C16H22ClN3O2 | 323.821 | 4 / 2 | 2.1 | Yes |
555899 | Renzapride | C16H22ClN3O2 | 323.821 | 4 / 2 | 2.1 | Yes |
553861 | Dau 6285 | C17H21N3O4 | 331.372 | 5 / 1 | 2.1 | Yes |
554081 | 5-METHOXYTRYPTAMINE | C11H14N2O | 190.246 | 2 / 2 | 0.5 | Yes |
554335 | GR 113808 | C19H27N3O4S | 393.502 | 6 / 1 | 1.7 | Yes |
554364 | BIMU-1 | C18H24N4O2 | 328.416 | 3 / 1 | 2.1 | Yes |
556337 | CHEMBL62023 | C18H24N4O2 | 328.416 | 3 / 1 | 2.1 | Yes |
554720 | serotonin | C10H12N2O | 176.219 | 2 / 3 | 0.2 | Yes |
556701 | CHEMBL293468 | C16H20N4O2 | 300.362 | 3 / 2 | 1.6 | Yes |
554870 | 144625-67-2 | C19H26FN3O5S | 427.491 | 8 / 2 | 2.2 | Yes |
554889 | metoclopramide | C14H22ClN3O2 | 299.799 | 4 / 2 | 2.6 | Yes |
335252 | CHEMBL325603 | C19H26N4O2 | 342.443 | 3 / 1 | 2.5 | Yes |
345205 | CHEMBL35226 | C21H29N3O | 339.483 | 4 / 1 | 4.5 | Yes |
555037 | RO 116 1148 | C19H28N2O3 | 332.444 | 4 / 1 | 2.9 | Yes |
557024 | RU-28253 | C14H16N2O | 228.295 | 2 / 2 | 1.8 | Yes |
557053 | 5-Carboxamidotryptamine | C11H13N3O | 203.245 | 2 / 3 | -0.6 | Yes |
557185 | R-76186 | C25H40ClN5O4 | 510.076 | 7 / 2 | 1.7 | No |
555330 | CHEMBL130040 | C19H27NO4 | 333.428 | 5 / 0 | 3.5 | Yes |
557246 | BDBM85018 | C19H29ClN3O2+ | 366.91 | 3 / 2 | 3.0 | Yes |
557269 | CHEMBL8197 | C17H20N2O2 | 284.359 | 3 / 1 | 3.8 | Yes |
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