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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL35226
Molecular formula	C21H29N3O
IUPAC name	5-[(1-propylpiperidin-4-yl)methoxy]-1,2,3,4-tetrahydrobenzo[h][1,6]naphthyridine
Molecular weight	339.483
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.5
Synonyms	5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahydro-benzo[h][1,6]naphthyridine BDBM50122716 L021962 6-(1-Propylpiperidine-4-ylmethoxy)-7,8,9,10-tetrahydro-10-azabenzo[c]quinoline
Inchi Key	UTMXFLLOSBJGIE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3
PubChem CID	9881053
ChEMBL	CHEMBL35226
IUPHAR	N/A
BindingDB	50122716
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
345215	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
345218	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
345208	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
345203	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
345202	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
345205	5-hydroxytryptamine receptor 4	P97288	Htr4	Mus musculus (Mouse)	388
345217	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
345212	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
345213	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
345216	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
345204	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
345209	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
345210	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
345207	Histamine H2 receptor	P25102	Hrh2	Rattus norvegicus (Rat)	358
345214	Vasopressin V1b receptor	P48974	Avpr1b	Rattus norvegicus (Rat)	425
345211	Vasopressin V2 receptor	P32307	AVPR2	Sus scrofa (Pig)	370

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