You can:
| Name | Histamine H2 receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Hrh2 |
| Synonym | gastric receptor I H2 receptor H2R HH2R |
| Disease | N/A for non-human GPCRs |
| Length | 358 |
| Amino acid sequence | MEPNGTVHSCCLDSMALKVTISVVLTTLILITIAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVLPFSAIYQLSFTWSFGHVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGLVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEAVEGIVLWLGYANSALNPILYAALNRDFRTAYQQLFHCKFASHNSHKTSLRLNNSLLPRSQSREGRWQEEKPLKLQVWSGTELTHPQGNPIR |
| UniProt | P25102 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4654 |
| IUPHAR | 263 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 11797 |  cimetidine | C10H16N6S | 252.34 | 4 / 3 | 0.4 | Yes |
| 14286 |  CHEMBL94917 | C29H35N5O7 | 565.627 | 7 / 6 | 2.0 | No |
| 14521 |  CHEMBL318221 | C26H36N4O8 | 532.594 | 8 / 6 | 2.1 | No |
| 26447 |  CHEMBL3228813 | C16H23N3O | 273.38 | 3 / 0 | 2.3 | Yes |
| 29620 |  CHEMBL3248393 | C10H19ClN6OS | 306.813 | 4 / 5 | N/A | N/A |
| 30652 |  CHEMBL3228800 | C14H19N3O2 | 261.325 | 4 / 0 | 1.5 | Yes |
| 31225 |  CHEMBL1790763 | C26H37N5O7 | 531.61 | 7 / 6 | 1.5 | No |
| 33252 |  CHEMBL282645 | C45H53N7O6 | 787.962 | 8 / 4 | 5.4 | No |
| 35439 |  CHEMBL328055 | C22H29N5O7 | 475.502 | 7 / 6 | -0.1 | No |
| 59407 |  proglumide | C18H26N2O4 | 334.416 | 4 / 2 | 2.4 | Yes |
| 63518 |  CHEMBL3228809 | C18H27N3O | 301.434 | 3 / 0 | 3.2 | Yes |
| 64287 |  CHEMBL278217 | C42H47N7O5 | 729.882 | 7 / 4 | 5.2 | No |
| 72502 |  CHEMBL330142 | C26H37N5O7 | 531.61 | 7 / 6 | 1.5 | No |
| 72503 |  CHEMBL96530 | C26H37N5O7 | 531.61 | 7 / 6 | 1.5 | No |
| 73121 |  CHEMBL262125 | C36H40N10O4S2 | 740.902 | 9 / 6 | 2.3 | No |
| 76015 |  CHEMBL3228792 | C14H19N3O | 245.326 | 3 / 0 | 1.7 | Yes |
| 82752 |  CHEMBL147889 | C9H16N4OS | 228.314 | 3 / 3 | -0.1 | Yes |
| 83341 |  CHEMBL265987 | C43H49N7O5 | 743.909 | 7 / 4 | 4.6 | No |
| 83736 |  CHEMBL3228812 | C15H21N3O | 259.353 | 3 / 0 | 1.9 | Yes |
| 83834 |  METIAMIDE | C9H16N4S2 | 244.375 | 3 / 3 | 0.5 | Yes |
| 92129 |  CHEMBL96681 | C27H39N5O7 | 545.637 | 7 / 6 | 1.8 | No |
| 92594 |  CHEMBL406844 | C43H49N7O6 | 759.908 | 8 / 4 | 4.9 | No |
| 103559 |  CHEMBL3228817 | C13H16N2O | 216.284 | 2 / 0 | 1.5 | Yes |
| 106423 |  CHEMBL17740 | C12H15N3 | 201.273 | 2 / 2 | 1.3 | Yes |
| 107948 |  CHEMBL285556 | C24H39N3O4 | 433.593 | 5 / 2 | 3.1 | Yes |
| 116192 |  1H-Imidazole-4-ethanamine, 1-(phenylmethyl)- | C12H15N3 | 201.273 | 2 / 1 | 1.0 | Yes |
| 117210 |  CHEMBL329524 | C25H37N5O5 | 487.601 | 5 / 5 | 2.3 | Yes |
| 123661 |  CHEMBL281082 | C34H36N10O4S2 | 712.848 | 9 / 6 | 2.5 | No |
| 123684 |  CHEMBL282646 | C44H51N7O6 | 773.935 | 8 / 4 | 5.1 | No |
| 126575 |  BURIMAMIDE | C9H16N4S | 212.315 | 2 / 3 | 0.4 | Yes |
| 131464 |  CHEMBL3228799 | C14H16F3N3O | 299.297 | 6 / 0 | 2.1 | Yes |
| 134722 |  CHEMBL33743 | C45H53N7O6 | 787.962 | 8 / 4 | 5.8 | No |
| 136411 |  CHEMBL281017 | C41H46N6O5 | 702.856 | 7 / 3 | 5.8 | No |
| 136805 |  CHEMBL3228793 | C15H21N3O | 259.353 | 3 / 0 | 2.0 | Yes |
| 144075 |  CHEMBL30430 | C32H33N9O3S2 | 655.796 | 8 / 5 | 2.7 | No |
| 150104 |  CHEMBL279778 | C46H55N7O5 | 785.99 | 7 / 4 | 5.7 | No |
| 150870 |  CHEMBL44345 | C27H38N6O8S | 606.695 | 9 / 7 | 0.3 | No |
| 151007 |  CHEMBL3228810 | C24H35N3O | 381.564 | 3 / 0 | 5.2 | No |
| 151535 |  CHEMBL3228815 | C15H22IN3O | 387.265 | 3 / 0 | N/A | N/A |
| 153389 |  CHEMBL3228805 | C13H17N3O | 231.299 | 3 / 1 | 1.1 | Yes |
| 164199 |  CHEMBL29331 | C46H55N7O5 | 785.99 | 7 / 4 | 6.2 | No |
| 165279 |  CHEMBL33819 | C43H49N7O6 | 759.908 | 8 / 4 | 5.2 | No |
| 166194 |  CHEMBL95063 | C25H33N5O7 | 515.567 | 7 / 5 | 1.2 | No |
| 167823 |  CHEMBL3228788 | C12H15N3O | 217.272 | 3 / 0 | 0.8 | Yes |
| 169517 |  CHEMBL3228789 | C13H17N3O | 231.299 | 3 / 0 | 1.2 | Yes |
| 170875 |  CHEMBL3220641 | C11H18N6 | 234.307 | 3 / 3 | 0.8 | Yes |
| 173261 |  CHEMBL3228818 | C14H21N3O | 247.342 | 3 / 0 | 1.3 | Yes |
| 173471 |  CHEMBL3228794 | C16H23N3O | 273.38 | 3 / 0 | 2.4 | Yes |
| 175173 |  CHEMBL280980 | C31H31N9O3S2 | 641.769 | 8 / 5 | 2.7 | No |
| 184084 |  CHEMBL3228798 | C14H16F3N3O | 299.297 | 6 / 0 | 2.1 | Yes |
| 186757 |  CHEMBL218375 | C26H29N3O5S | 495.594 | 6 / 2 | 4.2 | Yes |
| 187885 |  Amthamine | C6H11N3S | 157.235 | 4 / 2 | 0.4 | Yes |
| 188383 |  CHEMBL3228801 | C13H16ClN3O | 265.741 | 3 / 0 | 2.1 | Yes |
| 192402 |  CHEMBL3228814 | C16H23N3O | 273.38 | 3 / 0 | 2.2 | Yes |
| 202189 |  CHEMBL33412 | C48H59N9O6 | 858.057 | 10 / 4 | 4.6 | No |
| 204051 |  CHEMBL94448 | C29H42N6O8 | 602.689 | 8 / 7 | 1.2 | No |
| 211599 |  CHEMBL3228808 | C20H31N3O | 329.488 | 3 / 0 | 4.1 | Yes |
| 213915 |  CHEMBL3228804 | C12H15N3O | 217.272 | 3 / 1 | 0.6 | Yes |
| 215422 |  CHEMBL91765 | C29H35N5O7 | 565.627 | 7 / 6 | 1.9 | No |
| 215642 |  CHEMBL3228796 | C16H23N3O | 273.38 | 3 / 0 | 2.4 | Yes |
| 216968 |  CHEMBL284975 | C44H51N7O6 | 773.935 | 8 / 4 | 5.4 | No |
| 224779 |  CHEMBL2370238 | C32H45N5O9 | 643.738 | 9 / 6 | 3.2 | No |
| 232095 |  histamine | C5H9N3 | 111.148 | 2 / 2 | -0.7 | Yes |
| 232167 |  CHEMBL3228816 | C16H23N3O | 273.38 | 3 / 0 | 2.4 | Yes |
| 232412 |  CHEMBL30917 | C44H51N7O5 | 757.936 | 7 / 4 | 5.0 | No |
| 238665 |  CHEMBL3248392 | C9H18ClN5S | 263.788 | 3 / 4 | N/A | N/A |
| 243317 |  CHEMBL91752 | C29H42N6O8 | 602.689 | 8 / 7 | 1.3 | No |
| 249499 |  CHEMBL31090 | C44H51N7O5 | 757.936 | 7 / 4 | 5.4 | No |
| 251711 |  CHEMBL281318 | C38H44N10O4S2 | 768.956 | 9 / 6 | 3.0 | No |
| 252721 |  CHEMBL31671 | C39H42N6O4 | 658.803 | 6 / 3 | 5.4 | No |
| 252798 |  CHEMBL286475 | C43H49N7O5 | 743.909 | 7 / 4 | 5.1 | No |
| 254887 |  CHEMBL287295 | C44H51N7O6 | 773.935 | 8 / 4 | 5.7 | No |
| 257246 |  CHEMBL3248395 | C9H14N6S | 238.313 | 4 / 3 | -0.2 | Yes |
| 261106 |  CHEMBL30701 | C47H57N7O6 | 816.016 | 8 / 4 | 6.1 | No |
| 261861 |  Amselamine | C6H11N3Se | 204.146 | 3 / 2 | N/A | N/A |
| 263226 |  CHEMBL284183 | C40H44N6O4 | 672.83 | 6 / 3 | 5.3 | No |
| 269222 |  CHEMBL29888 | C33H35N9O4S2 | 685.822 | 9 / 5 | 3.1 | No |
| 269234 |  CHEMBL33398 | C45H52N8O7 | 816.96 | 9 / 5 | 4.4 | No |
| 271614 |  CHEMBL289310 | C25H35N5O7S | 549.643 | 8 / 6 | 0.8 | No |
| 277354 |  CHEMBL328512 | C28H40N6O8S | 620.722 | 9 / 7 | 0.5 | No |
| 279607 |  Benzotript | C18H15ClN2O3 | 342.779 | 3 / 3 | 2.9 | Yes |
| 299254 |  CHEMBL286908 | C35H38N10O4S2 | 726.875 | 9 / 6 | 2.4 | No |
| 301172 |  BCTC | C20H25ClN4O | 372.897 | 3 / 1 | 4.3 | Yes |
| 302413 |  abt-702 | C22H19BrN6O | 463.339 | 7 / 1 | 3.4 | Yes |
| 305567 |  CHEMBL30821 | C35H38N10O4S2 | 726.875 | 9 / 6 | 1.9 | No |
| 308120 |  CHEMBL3228811 | C21H31N3O | 341.499 | 3 / 0 | 3.7 | Yes |
| 310615 |  CHEMBL3228819 | C14H23N3 | 233.359 | 3 / 0 | 2.5 | Yes |
| 312427 |  CHEMBL1077862 | C10H16N6 | 220.28 | 3 / 3 | 0.0 | Yes |
| 320823 |  CHEMBL30656 | C35H38N10O5S2 | 742.874 | 10 / 6 | 2.5 | No |
| 329003 |  CHEMBL30195 | C40H44N6O4 | 672.83 | 6 / 3 | 5.8 | No |
| 329681 |  CHEMBL380492 | C34H40ClN3O4 | 590.161 | 6 / 2 | 3.7 | No |
| 554915 |  1-[4-(1H-indazol-4-yl)butyl]-3-methylthiourea | C13H18N4S | 262.375 | 2 / 3 | 2.3 | Yes |
| 330865 |  CHEMBL285746 | C32H33N9O3S2 | 655.796 | 8 / 5 | 3.2 | No |
| 333985 |  CHEMBL285719 | C49H61N9O6 | 872.084 | 10 / 4 | 4.9 | No |
| 334798 |  CHEMBL286907 | C36H40N10O4S2 | 740.902 | 9 / 6 | 2.8 | No |
| 339136 |  4-Methylburimamide | C10H18N4S | 226.342 | 2 / 3 | 0.8 | Yes |
| 340945 |  CHEMBL3228820 | C14H19N3S | 261.387 | 3 / 0 | 2.2 | Yes |
| 345207 |  CHEMBL35226 | C21H29N3O | 339.483 | 4 / 1 | 4.5 | Yes |
| 346033 |  CHEMBL3228802 | C15H21N3O | 259.353 | 3 / 0 | 1.9 | Yes |
| 349251 |  CHEMBL290122 | C45H53N7O6 | 787.962 | 8 / 4 | 5.7 | No |
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