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GPCR

NameHistamine H2 receptor
SpeciesRattus norvegicus (Rat)
GeneHrh2
Synonymgastric receptor I
H2 receptor
H2R
HH2R
DiseaseN/A for non-human GPCRs
Length358
Amino acid sequenceMEPNGTVHSCCLDSMALKVTISVVLTTLILITIAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVLPFSAIYQLSFTWSFGHVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGLVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEAVEGIVLWLGYANSALNPILYAALNRDFRTAYQQLFHCKFASHNSHKTSLRLNNSLLPRSQSREGRWQEEKPLKLQVWSGTELTHPQGNPIR
UniProtP25102
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4654
IUPHAR263
DrugBankN/A

Ligand

NameAmselamine
Molecular formulaC6H11N3Se
IUPAC name5-(2-aminoethyl)-4-methyl-1,3-selenazol-2-amine
Molecular weight204.146
Hydrogen bond acceptor3
Hydrogen bond donor2
XlogPNone
SynonymsCHEMBL60686
5-(2-aminoethyl)-4-methyl-1,3-selenazol-2-amine
2-amino-5(2-aminoethyl)-4-methyl-1,3-selenazole
CHEMBL1632408
BDBM22882
Inchi KeyPKGAPIBVLGICCE-UHFFFAOYSA-N
Inchi IDInChI=1S/C6H11N3Se/c1-4-5(2-3-7)10-6(8)9-4/h2-3,7H2,1H3,(H2,8,9)
PubChem CID9990475
ChEMBLCHEMBL1632408
IUPHARN/A
BindingDB22882
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessPartition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
Kd9772.0 nMN/ABindingDB

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