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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Amthamine
Molecular formula	C6H11N3S
IUPAC name	5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine
Molecular weight	157.235
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	0.4
Synonyms	BRD-K39670393-303-01-3 GTPL4025 SCHEMBL400272 5-Thiazoleethanamine, 2-amino-4-methyl- CHEMBL293762 L000107 2-Amino-5-(2-aminoethyl)-4-methylthiazole DTXSID80162039 RL01758 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine CHEBI:92694 J-007652 Tocris-0668 142437-67-0 AC1L2QR3 CTK8E9579 NCGC00024719-01 BDBM22881 FT-0694778 RT-011284 5-(2-aminoethyl)-4-methylthiazol-2-amine KB-47389 ZINC5099 2-AMINO-4-METHYLTHIAZOLE-5-ETHANAMINE AKOS006271424 D0I5CT NCGC00024719-02 [ Show all ]
Inchi Key	LHVRFUVVRXGZPV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C6H11N3S/c1-4-5(2-3-7)10-6(8)9-4/h2-3,7H2,1H3,(H2,8,9)
PubChem CID	126688
ChEMBL	CHEMBL293762
IUPHAR	4025
BindingDB	22881
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
187888	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
187885	Histamine H2 receptor	P25102	Hrh2	Rattus norvegicus (Rat)	358
187886	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
187887	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
187889	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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