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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL380492
Molecular formula	C34H40ClN3O4
IUPAC name	2-[4-[[1-[[3-(2-chlorophenoxy)phenyl]methyl]piperidin-4-yl]carbamoyl]-4-phenylpiperidin-1-yl]-2-methylpropanoic acid
Molecular weight	590.161
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.7
Synonyms	SCHEMBL6506018 2-(4-{1-[3-(2-chloro-phenoxy)-benzyl]-piperidin-4-ylcarbamoyl}-4-phenyl-piperidin-1-yl)-2-methyl-propionic acid BDBM50185912
Inchi Key	TXEFMFGXKKPZEW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H40ClN3O4/c1-33(2,32(40)41)38-21-17-34(18-22-38,26-10-4-3-5-11-26)31(39)36-27-15-19-37(20-16-27)24-25-9-8-12-28(23-25)42-30-14-7-6-13-29(30)35/h3-14,23,27H,15-22,24H2,1-2H3,(H,36,39)(H,40,41)
PubChem CID	11685733
ChEMBL	CHEMBL380492
IUPHAR	N/A
BindingDB	50185912
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
329685	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
329678	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
329677	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
329684	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
329680	C-C chemokine receptor type 8	P51685	CCR8	Homo sapiens (Human)	355
329682	Cholecystokinin receptor type A	P30551	Cckar	Rattus norvegicus (Rat)	444
329679	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
329683	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
329681	Histamine H2 receptor	P25102	Hrh2	Rattus norvegicus (Rat)	358

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