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| Name | C-C chemokine receptor type 3 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | CCR3 |
| Synonym | MIP-1alphaRL-2 (mouse) Eosinophil eotaxin receptor CKR3 chemokine (C-C motif) receptor 3 CD193 [ Show all ] |
| Disease | Allergic asthma Allergic rhinitis Asthma |
| Length | 355 |
| Amino acid sequence | MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF |
| UniProt | P51677 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P51677 |
| 3D structure model | This predicted structure model is from GPCR-EXP P51677. |
| BioLiP | N/A |
| Therapeutic Target Database | T02752, T85228 |
| ChEMBL | CHEMBL3473 |
| IUPHAR | 60 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 183 |  CHEMBL363194 | C25H30Cl3N3O | 494.885 | 3 / 1 | 6.0 | No |
| 1178 |  CHEMBL403743 | C31H42FN5O4S | 599.766 | 8 / 2 | 3.8 | No |
| 463108 |  CHEMBL3706812 | C27H34FN5O | 463.601 | 4 / 3 | 5.0 | Yes |
| 1625 |  CHEMBL497202 | C26H32F3N3O4S2 | 571.674 | 9 / 2 | 4.1 | No |
| 1863 |  CHEMBL416835 | C24H28FN3O | 393.506 | 4 / 1 | 3.9 | Yes |
| 2298 |  CHEMBL253210 | C26H34FN7O | 479.604 | 6 / 2 | 4.4 | Yes |
| 2307 |  CHEMBL564022 | C29H29ClFN3O3 | 522.017 | 5 / 2 | 5.0 | No |
| 3081 |  CHEMBL488529 | C30H32FN3O3 | 501.602 | 5 / 1 | 4.3 | No |
| 3385 |  CHEMBL220801 | C26H34FN3O3 | 455.574 | 5 / 3 | 3.5 | Yes |
| 3919 |  CHEMBL2171022 | C25H28Cl2N2O5 | 507.408 | 6 / 1 | 2.7 | No |
| 5271 |  CHEMBL194435 | C29H38N4 | 442.651 | 4 / 1 | 5.4 | No |
| 5555 |  CHEMBL195291 | C26H33F3N4O | 474.572 | 6 / 2 | 5.0 | Yes |
| 5704 |  CHEMBL562923 | C29H30FN3O3 | 487.575 | 5 / 2 | 3.8 | Yes |
| 6562 |  CHEMBL491611 | C30H34FN3O | 471.62 | 4 / 1 | 6.2 | No |
| 7255 |  CHEMBL2208426 | C20H24Cl2N2O5S2 | 507.441 | 7 / 2 | 3.7 | No |
| 7466 |  CHEMBL217928 | C28H33F4N3O3 | 535.584 | 8 / 2 | 5.0 | No |
| 7623 |  CHEMBL399045 | C26H29Cl3N2O | 491.881 | 2 / 0 | 6.7 | No |
| 8079 |  CHEMBL2088381 | C30H39F3N4O3S | 592.722 | 8 / 2 | 6.0 | No |
| 8435 |  CHEMBL2057760 | C34H39FN4O2 | 554.71 | 4 / 1 | 5.2 | No |
| 8812 |  CHEMBL2207284 | C25H28Cl2N4O6S | 583.481 | 8 / 4 | 2.2 | No |
| 9160 |  CHEMBL2208420 | C21H22Cl2N2O2 | 405.319 | 4 / 0 | 5.5 | No |
| 9462 |  CHEMBL519750 | C31H34FN3O2 | 499.63 | 4 / 1 | 5.6 | No |
| 10277 |  CHEMBL50591 | C24H35N3O | 381.564 | 3 / 1 | 4.3 | Yes |
| 10469 |  CHEMBL181678 | C26H32ClFN2O | 443.003 | 3 / 0 | 5.7 | No |
| 11402 |  CHEMBL262918 | C23H27F4N3O | 437.483 | 6 / 2 | 5.0 | Yes |
| 11782 |  CHEMBL246339 | C32H34ClF2N5O2 | 594.104 | 7 / 1 | 5.6 | No |
| 11801 |  CHEMBL2171045 | C24H26Cl2F3N3O4S | 580.444 | 8 / 1 | 5.6 | No |
| 11934 |  CHEMBL500786 | C29H36F3N3O6S2 | 643.737 | 10 / 3 | 5.7 | No |
| 12132 |  CHEMBL2158791 | C28H36ClFN2O3 | 503.055 | 6 / 1 | 3.9 | No |
| 12660 |  CHEMBL49921 | C28H39N3O3 | 465.638 | 4 / 3 | 4.4 | Yes |
| 12839 |  CHEMBL126163 | C29H29FN4O3 | 500.574 | 6 / 2 | 4.7 | No |
| 12887 |  CHEMBL178136 | C29H33Cl2N3O | 510.503 | 3 / 0 | 7.0 | No |
| 464485 |  CHEMBL3706810 | C27H34FN5O | 463.601 | 4 / 3 | 5.1 | No |
| 13448 |  CHEMBL370082 | C28H36FN3O2 | 465.613 | 4 / 2 | 5.2 | No |
| 13450 |  CHEMBL250689 | C28H36FN3O2 | 465.613 | 4 / 2 | 5.2 | No |
| 13881 |  CHEMBL43656 | C24H30N4O | 390.531 | 3 / 2 | 4.1 | Yes |
| 14178 |  CHEMBL2171021 | C25H30Cl2N2O4S | 525.485 | 5 / 0 | 5.1 | No |
| 14414 |  CHEMBL361761 | C18H14ClN3 | 307.781 | 2 / 1 | 3.7 | Yes |
| 14640 |  CHEMBL361430 | C20H20BrN3S | 414.365 | 3 / 1 | 5.5 | No |
| 15057 |  CHEMBL341343 | C27H28N4O2 | 440.547 | 4 / 3 | 4.4 | Yes |
| 15074 |  CHEMBL176077 | C27H36FN3O | 437.603 | 3 / 2 | 5.8 | No |
| 16105 |  CHEMBL247455 | C30H41F3N6O4 | 606.691 | 8 / 6 | 3.9 | No |
| 16489 |  CHEMBL181273 | C27H30Cl2N4O2 | 513.463 | 5 / 0 | 5.4 | No |
| 17079 |  CHEMBL51052 | C27H37N3O3 | 451.611 | 4 / 3 | 3.7 | Yes |
| 17478 |  CHEMBL193592 | C25H27FN4O | 418.516 | 4 / 2 | 4.2 | Yes |
| 17550 |  CHEMBL123611 | C30H33FN4O3 | 516.617 | 5 / 3 | 4.1 | No |
| 17602 |  CHEMBL249857 | C27H37FN6O3S | 544.69 | 7 / 3 | 3.3 | No |
| 17662 |  CHEMBL2158790 | C28H35Cl2FN2O3 | 537.497 | 6 / 1 | 4.5 | No |
| 17701 |  CHEMBL2088385 | C34H39F3N4O3S | 640.766 | 8 / 2 | 6.5 | No |
| 18069 |  CHEMBL123957 | C27H28N4O | 424.548 | 3 / 2 | 4.7 | Yes |
| 18349 |  CHEMBL126520 | C29H32FN3O4 | 505.59 | 6 / 2 | 4.9 | No |
| 18368 |  CHEMBL221903 | C27H34FN3O2 | 451.586 | 4 / 2 | 4.9 | Yes |
| 18494 |  CHEMBL247160 | C32H33ClF2N4O2 | 579.089 | 6 / 0 | 6.3 | No |
| 18667 |  CHEMBL50194 | C29H41N7O2 | 519.694 | 6 / 3 | 4.6 | No |
| 19040 |  CHEMBL269898 | C25H30F3N3O2 | 461.529 | 6 / 3 | 4.6 | Yes |
| 19042 |  CHEMBL406925 | C25H30F3N3O2 | 461.529 | 6 / 3 | 4.6 | Yes |
| 19086 |  CHEMBL193656 | C28H36N4 | 428.624 | 4 / 1 | 5.0 | Yes |
| 19170 |  CHEMBL2158778 | C26H32ClFN2O3 | 475.001 | 6 / 1 | 3.3 | Yes |
| 19286 |  CHEMBL36473 | C25H22N4O4S | 474.535 | 6 / 2 | 4.8 | Yes |
| 19290 |  CHEMBL123308 | C27H34Cl2N2O | 473.482 | 2 / 1 | 7.6 | No |
| 19387 |  CHEMBL261449 | C23H24FN3O | 377.463 | 3 / 2 | 4.4 | Yes |
| 19483 |  CHEMBL32413 | C19H21NO3 | 311.381 | 3 / 1 | 3.8 | Yes |
| 20373 |  CHEMBL2057753 | C31H36FN5O2 | 529.66 | 5 / 2 | 4.2 | No |
| 20471 |  CHEMBL194715 | C26H33F3N4O | 474.572 | 6 / 2 | 5.0 | Yes |
| 20524 |  CHEMBL181379 | C29H33Cl2N3O2 | 526.502 | 4 / 0 | 6.1 | No |
| 22099 |  SB297006 | C18H18N2O5 | 342.351 | 5 / 1 | 3.3 | Yes |
| 22308 |  CHEMBL20532 | C21H21Cl2N3OS2 | 466.439 | 5 / 1 | 5.9 | No |
| 22990 |  CHEMBL124583 | C26H27F2N3O | 435.519 | 4 / 2 | 5.2 | No |
| 23379 |  CHEMBL398889 | C29H40FN5O2S | 541.73 | 7 / 2 | 4.8 | No |
| 23915 |  CHEMBL193871 | C27H38N4O3 | 466.626 | 5 / 2 | 4.1 | Yes |
| 24463 |  CHEMBL253209 | C25H32FN7O | 465.577 | 6 / 3 | 4.5 | Yes |
| 24509 |  CHEMBL195657 | C31H41N3O | 471.689 | 4 / 1 | 6.6 | No |
| 24648 |  CHEMBL258309 | C27H34FN3O4 | 483.584 | 6 / 3 | 3.4 | Yes |
| 24649 |  CHEMBL256068 | C27H34FN3O4 | 483.584 | 6 / 3 | 3.4 | Yes |
| 24900 |  CHEMBL419599 | C30H33FIN3O4 | 645.514 | 6 / 2 | N/A | No |
| 25303 |  CHEMBL193354 | C28H32Cl2N4O | 511.491 | 4 / 1 | 5.6 | No |
| 25348 |  CHEMBL181789 | C29H34Cl2N4O3S | 589.576 | 6 / 1 | 5.2 | No |
| 25707 |  CHEMBL123622 | C32H40ClN3O2 | 534.141 | 3 / 3 | 6.1 | No |
| 25749 |  CHEMBL299385 | C23H27F4N3O | 437.483 | 6 / 2 | 5.0 | Yes |
| 26009 |  CHEMBL51307 | C22H29N3O | 351.494 | 2 / 2 | 4.0 | Yes |
| 26127 |  CHEMBL178447 | C28H31Cl2N3O2 | 512.475 | 4 / 1 | 5.4 | No |
| 26716 |  CHEMBL192751 | C27H35F3N4O | 488.599 | 6 / 2 | 5.4 | No |
| 27236 |  SCHEMBL1670687 | C29H36ClN5O4 | 554.088 | 6 / 1 | 2.6 | No |
| 28812 |  CHEMBL1910161 | C25H28BrFN2O2 | 487.413 | 4 / 1 | 5.1 | No |
| 28823 |  CHEMBL290276 | C26H32FN3O2 | 437.559 | 4 / 2 | 4.2 | Yes |
| 442862 |  CHEMBL282871 | C19H22N4OS3 | 418.592 | 7 / 1 | 3.9 | Yes |
| 30603 |  AC1LA88L | C37H43N5O4 | 621.782 | 5 / 2 | 5.7 | No |
| 31114 |  CHEMBL365596 | C30H45N3 | 447.711 | 3 / 1 | 6.6 | No |
| 31215 |  CHEMBL338624 | C36H37ClF3N3O2 | 636.156 | 6 / 3 | 7.8 | No |
| 31290 |  CHEMBL33589 | C23H22N2O5 | 406.438 | 5 / 1 | 5.0 | Yes |
| 31343 |  CHEMBL385607 | C28H35FN4O4 | 510.61 | 6 / 3 | 2.9 | No |
| 31478 |  CHEMBL194135 | C27H36F3N3 | 459.601 | 6 / 1 | 5.8 | No |
| 32160 |  CHEMBL51480 | C26H34FN3O2 | 439.575 | 4 / 1 | 4.8 | Yes |
| 34104 |  CHEMBL252222 | C23H31N7O3 | 453.547 | 7 / 4 | 1.4 | Yes |
| 34105 |  CHEMBL254503 | C23H31N7O3 | 453.547 | 7 / 4 | 1.4 | Yes |
| 34106 |  CHEMBL252221 | C23H31N7O3 | 453.547 | 7 / 4 | 1.4 | Yes |
| 34107 |  CHEMBL252628 | C23H31N7O3 | 453.547 | 7 / 4 | 1.4 | Yes |
| 35003 |  CHEMBL49296 | C23H29FN2O | 368.496 | 3 / 1 | 4.8 | Yes |
| 35812 |  CHEMBL290119 | C22H21NO4 | 363.413 | 4 / 2 | 4.4 | Yes |
| 35852 |  CHEMBL51937 | C30H41FN4O4 | 540.68 | 6 / 1 | 4.6 | No |
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