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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor type 3
Species	Homo sapiens (Human)
Gene	CCR3
Synonym	MIP-1alphaRL-2 (mouse) Eosinophil eotaxin receptor CKR3 chemokine (C-C motif) receptor 3 CD193 CCR3 CCR-3 CC-CKR-3 CC CKR3 C-C CKR-3 [ Show all ]
Disease	Allergic asthma Allergic rhinitis Asthma
Length	355
Amino acid sequence	MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
UniProt	P51677
Protein Data Bank	N/A
GPCR-HGmod model	P51677
3D structure model	This predicted structure model is from GPCR-EXP P51677.
BioLiP	N/A
Therapeutic Target Database	T02752, T85228
ChEMBL	CHEMBL3473
IUPHAR	60
DrugBank	N/A

Ligand

Name	CHEMBL261449
Molecular formula	C23H24FN3O
IUPAC name	1-[1-[(6-fluoronaphthalen-2-yl)methyl]piperidin-4-yl]-3-phenylurea
Molecular weight	377.463
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.4
Synonyms	N/A
Inchi Key	BBCPRDBWRQVCQW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H24FN3O/c24-20-9-8-18-14-17(6-7-19(18)15-20)16-27-12-10-22(11-13-27)26-23(28)25-21-4-2-1-3-5-21/h1-9,14-15,22H,10-13,16H2,(H2,25,26,28)
PubChem CID	44452146
ChEMBL	CHEMBL261449
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	31.0 %	PMID17951061	ChEMBL

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