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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL246339
Molecular formula	C32H34ClF2N5O2
IUPAC name	2-(4-aminophenyl)-4-[[2-(4-chlorophenyl)ethyl-[1-(2,6-difluorobenzoyl)piperidin-4-yl]amino]methyl]-1,5-dimethylpyrazol-3-one
Molecular weight	594.104
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.6
Synonyms	BDBM50214133 SCHEMBL18840974 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-aminophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one
Inchi Key	AQIPJIQPPWTJAY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H34ClF2N5O2/c1-21-27(31(41)40(37(21)2)26-12-10-24(36)11-13-26)20-39(17-14-22-6-8-23(33)9-7-22)25-15-18-38(19-16-25)32(42)30-28(34)4-3-5-29(30)35/h3-13,25H,14-20,36H2,1-2H3
PubChem CID	44440421
ChEMBL	CHEMBL246339
IUPHAR	N/A
BindingDB	50214133
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11782	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355

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