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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor type 3
Species	Homo sapiens (Human)
Gene	CCR3
Synonym	MIP-1alphaRL-2 (mouse) Eosinophil eotaxin receptor CKR3 chemokine (C-C motif) receptor 3 CD193 CCR3 CCR-3 CC-CKR-3 CC CKR3 C-C CKR-3 [ Show all ]
Disease	Allergic asthma Allergic rhinitis Asthma
Length	355
Amino acid sequence	MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
UniProt	P51677
Protein Data Bank	N/A
GPCR-HGmod model	P51677
3D structure model	This predicted structure model is from GPCR-EXP P51677.
BioLiP	N/A
Therapeutic Target Database	T02752, T85228
ChEMBL	CHEMBL3473
IUPHAR	60
DrugBank	N/A

Ligand

Name	CHEMBL282871
Molecular formula	C19H22N4OS3
IUPAC name	2-(1,3-benzothiazol-2-ylsulfanyl)-N-[[1-(1,3-thiazol-2-ylmethyl)piperidin-3-yl]methyl]acetamide
Molecular weight	418.592
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.9
Synonyms	N-[1-(2-Thiazolylmethyl)piperidine-3-ylmethyl](benzothiazole-2-ylthio)acetamide SCHEMBL18840710
Inchi Key	BQQZZRPDNHIKAA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H22N4OS3/c24-17(13-26-19-22-15-5-1-2-6-16(15)27-19)21-10-14-4-3-8-23(11-14)12-18-20-7-9-25-18/h1-2,5-7,9,14H,3-4,8,10-13H2,(H,21,24)
PubChem CID	11742790
ChEMBL	CHEMBL282871
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	0.0 %	PMID11354381	ChEMBL

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