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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL247160
Molecular formula	C32H33ClF2N4O2
IUPAC name	4-[[2-(4-chlorophenyl)ethyl-[1-(2,6-difluorobenzoyl)piperidin-4-yl]amino]methyl]-1,5-dimethyl-2-phenylpyrazol-3-one
Molecular weight	579.089
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	6.3
Synonyms	BDBM50214123 SCHEMBL18840972 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-1,5-dimethyl-2-phenyl-1,2-dihydropyrazol-3-one
Inchi Key	AZTSGCZWMJWVIL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H33ClF2N4O2/c1-22-27(31(40)39(36(22)2)26-7-4-3-5-8-26)21-38(18-15-23-11-13-24(33)14-12-23)25-16-19-37(20-17-25)32(41)30-28(34)9-6-10-29(30)35/h3-14,25H,15-21H2,1-2H3
PubChem CID	44440394
ChEMBL	CHEMBL247160
IUPHAR	N/A
BindingDB	50214123
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18494	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355

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