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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL178447
Molecular formula	C28H31Cl2N3O2
IUPAC name	[4-[(3S,4S)-4-[(3,4-dichlorophenyl)methyl]-3-(hydroxymethyl)piperidin-1-yl]piperidin-1-yl]-quinolin-6-ylmethanone
Molecular weight	512.475
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.4
Synonyms	SCHEMBL13389597 [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-hydroxymethyl-[1,4'''']bipiperidinyl-1''''-yl]-quinolin-6-yl-methanone BDBM50161407
Inchi Key	BKSRLDUBSLBPQQ-OFNKIYASSA-N
Inchi ID	InChI=1S/C28H31Cl2N3O2/c29-25-5-3-19(15-26(25)30)14-20-7-11-33(17-23(20)18-34)24-8-12-32(13-9-24)28(35)22-4-6-27-21(16-22)2-1-10-31-27/h1-6,10,15-16,20,23-24,34H,7-9,11-14,17-18H2/t20-,23+/m1/s1
PubChem CID	11466397
ChEMBL	CHEMBL178447
IUPHAR	N/A
BindingDB	50161407
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
26127	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
26128	C-C chemokine receptor type 3	P56483	CCR3	Macaca mulatta (Rhesus macaque)	355
26129	C-C chemokine receptor type 3	O54814	Ccr3	Rattus norvegicus (Rat)	359
26126	Probable C-C chemokine receptor type 3	P51678	Ccr3	Mus musculus (Mouse)	359

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