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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL181273
Molecular formula	C27H30Cl2N4O2
IUPAC name	[4-[(3S,4S)-4-[(3,4-dichlorophenyl)methyl]-3-methoxypiperidin-1-yl]piperidin-1-yl]-(1,8-naphthyridin-2-yl)methanone
Molecular weight	513.463
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	5.4
Synonyms	BDBM50161432 SCHEMBL13407639 [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'''']bipiperidinyl-1''''-yl]-[1,8]naphthyridin-2-yl-methanone
Inchi Key	AXAAKILJQSGHDI-CJFMBICVSA-N
Inchi ID	InChI=1S/C27H30Cl2N4O2/c1-35-25-17-33(12-8-20(25)15-18-4-6-22(28)23(29)16-18)21-9-13-32(14-10-21)27(34)24-7-5-19-3-2-11-30-26(19)31-24/h2-7,11,16,20-21,25H,8-10,12-15,17H2,1H3/t20-,25-/m1/s1
PubChem CID	11283679
ChEMBL	CHEMBL181273
IUPHAR	N/A
BindingDB	50161432
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16489	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355

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