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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL218375
Molecular formula	C26H29N3O5S
IUPAC name	ethyl 4-[[4-[(2-methylbenzoyl)amino]naphthalen-1-yl]sulfonylamino]piperidine-1-carboxylate
Molecular weight	495.594
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.2
Synonyms	BDBM50203881 SCHEMBL1339287 4-[4-(2-methyl-benzoylamino)-naphthalene-1-sulfonylamino]-piperidine-1-carboxylic acid ethyl ester
Inchi Key	LGJRRERRFSZFTJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H29N3O5S/c1-3-34-26(31)29-16-14-19(15-17-29)28-35(32,33)24-13-12-23(21-10-6-7-11-22(21)24)27-25(30)20-9-5-4-8-18(20)2/h4-13,19,28H,3,14-17H2,1-2H3,(H,27,30)
PubChem CID	16105788
ChEMBL	CHEMBL218375
IUPHAR	N/A
BindingDB	50203881
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
186752	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
186760	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
186754	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
186755	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
186753	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
186756	C-C chemokine receptor type 8	P51685	CCR8	Homo sapiens (Human)	355
186759	Cholecystokinin receptor type A	P30551	Cckar	Rattus norvegicus (Rat)	444
186761	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
186758	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
186757	Histamine H2 receptor	P25102	Hrh2	Rattus norvegicus (Rat)	358

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