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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	METIAMIDE
Molecular formula	C9H16N4S2
IUPAC name	1-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]thiourea
Molecular weight	244.375
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	0.5
Synonyms	MolPort-002-801-395 N-methyl-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]thiourea NSC-307755 SCHEMBL534307 3-Methyl-1-(2-((5-methyl-4-imidazolyl)methylthio)ethyl)thiourea W-5324 AC1LU7MD BDBM50000382 CS-1294 HY-15540 Metiamida [INN-Spanish] Metiamide HCl N-Methyl-N'-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)thiourea # N-methyl-N'-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]thiourea PDSP1_000614 1-Methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)-2-thiourea SKF 92058 3K7670861M AJ-54031 C9H16N4S2 L023988 Metiamidum N-methyl-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl] thiourea N-Methyl-N'-[2-[[(5-methylimidazol-4-yl)methyl]thio]ethyl]thiourea SC-94342 1-Methyl-3-[2-[[(5-methylimidazol-4-yl)methyl]thio]ethyl]-2-thiourea UNII-3K7670861M AX8140020 FPBPLBWLMYGIQR-UHFFFAOYSA-N Methiamide MolPort-018-684-840 N-methyl-N'-[2-((5-methyl-4-imidazolyl)-methylthio)ethyl]thiourea NSC307755 SK&F 92058 3-methyl-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]thiourea ZINC5424950 ACM34839708 BDBM81468 D05004 J-522704 Metiamide [USAN:BAN:INN] N-methyl-N'-(2-{[(4-methyl-1H-imidazol-5-yl)methyl]sulfanyl}ethyl)thiourea N-methyl-N'-[2-(5-methyl-4-imidazolylmethylthio)ethyl]thiourea PDSP2_000611 1-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]thiourea Thiourea, N-methyl-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)- 4243AB AKOS005065704 CAS_34839-70-8 DB08805 LS-160472 Metiamidum [INN-Latin] N-methyl-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]-thiourea NSC 307755 SCHEMBL11363901 Urea, 1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)-2-thio- BCP21503 CHEMBL275446 GTPL1233 Metiamida N-Methyl-N'-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)thiourea N-methyl-N'-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]-thiourea NSC_1548992 1-Methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)thiourea SK&F-92058 34839-70-8 AE-641/30115027 C07449 D0W9LJ KB-219225 Metiamide (USAN/INN) Metiamide [USAN:INN:BAN] N-methyl-N'-[2-((4-methyl-5-imidazolyl)methylthio)-ethyl]thiourea N-methyl-N'-[2-(5-methylimidazol-4-yl)methylthioethyl] thiourea RL03297 1-Methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]thiourea;1-methyl-3-(2-((5-methyl-1H-imidazol-4-yl)methylthio)ethyl)thiourea Thiourea, N-methyl-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]- 4CA-0813 API0007627 CHEBI:6896 DTXSID80188390 MCULE-4285442691 [ Show all ]
Inchi Key	FPBPLBWLMYGIQR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C9H16N4S2/c1-7-8(13-6-12-7)5-15-4-3-11-9(14)10-2/h6H,3-5H2,1-2H3,(H,12,13)(H2,10,11,14)
PubChem CID	1548992
ChEMBL	CHEMBL275446
IUPHAR	1233
BindingDB	50000382, 81468
DrugBank	DB08805
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
83831	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
83832	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
83830	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
83834	Histamine H2 receptor	P25102	Hrh2	Rattus norvegicus (Rat)	358
83835	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
83833	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445

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