You can:
| Name | Histamine H1 receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Hrh1 |
| Synonym | H1 receptor H1R HH1R Hisr |
| Disease | N/A for non-human GPCRs |
| Length | 486 |
| Amino acid sequence | MSFANTSSTFEDKMCEGNRTAMASPQLLPLVVVLSSISLVTVGLNLLVLYAVHSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLIMTKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWFFSFLWVIPILGWHHFMPPAPELREDKCETDFYNVTWFKIMTAIINFYLPTLLMLWFYVKIYKAVRRHCQHRQLTNGSLPSFSELKLRSDDTKEGAKKPGRESPWGVLKRPSRDPSVGLDQKSTSEDPKMTSPTVFSQEGERETRPCFRLDIMQKQSVAEGDVRGSKANDQALSQPKMDEQSLNTCRRISETSEDQTLVDQQSFSRTTDSDTSIEPGPGRVKSRSGSNSGLDYIKITWKRLRSHSRQYVSGLHLNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKSCCSEPMHMFTIWLGYINSTLNPLIYPLCNENFKKTFKKILHIRS |
| UniProt | P31390 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4701 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 80 |  Eticlopride | C17H25ClN2O3 | 340.848 | 4 / 2 | 3.1 | Yes |
| 3125 |  AC1N0YGA | C3H7NO4S | 153.152 | 5 / 2 | -4.7 | Yes |
| 5761 |  paroxetine | C19H20FNO3 | 329.371 | 5 / 1 | 3.5 | Yes |
| 6144 |  CHEMBL2448125 | C20H22ClN3O | 355.866 | 3 / 0 | 2.6 | Yes |
| 6145 |  CHEMBL2111767 | C20H22ClN3O | 355.866 | 3 / 0 | 2.6 | Yes |
| 6146 |  CHEMBL326821 | C20H22ClN3O | 355.866 | 3 / 0 | 2.6 | Yes |
| 9593 |  CHEMBL444827 | C21H23ClN4O | 382.892 | 3 / 2 | 3.3 | Yes |
| 11579 |  CHEMBL332936 | C19H20ClN3O | 341.839 | 3 / 0 | 2.6 | Yes |
| 15053 |  5-HT4 antagonist 1 | C23H36N4O5S | 480.624 | 8 / 1 | 1.2 | Yes |
| 19095 |  CHEMBL536747 | C35H46ClF2N3 | 582.221 | 5 / 1 | N/A | No |
| 20166 |  imipramine | C19H24N2 | 280.415 | 2 / 0 | 4.8 | Yes |
| 21230 |  (RS)-PPCC | C24H29NO3 | 379.5 | 4 / 1 | 3.5 | Yes |
| 23361 |  sulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 24121 |  CHEMBL15637 | C23H27Cl2N3OS | 464.449 | 4 / 0 | 5.4 | No |
| 28670 |  CHEMBL61348 | C21H24ClN5 | 381.908 | 3 / 2 | 3.0 | Yes |
| 30037 |  Histaprodifen | C20H23N3 | 305.425 | 2 / 2 | 3.5 | Yes |
| 32459 |  CHEMBL58549 | C20H21ClN4O | 368.865 | 3 / 2 | 3.0 | Yes |
| 33428 |  CHEMBL140919 | C19H19ClN2O | 326.824 | 2 / 0 | 3.5 | Yes |
| 33812 |  CHEMBL333594 | C21H24ClN3O | 369.893 | 3 / 0 | 3.0 | Yes |
| 34624 |  protriptyline | C19H21N | 263.384 | 1 / 1 | 4.4 | Yes |
| 35222 |  CHEMBL557585 | C35H45F2N3 | 545.763 | 5 / 0 | 7.5 | No |
| 37803 |  triprolidine | C19H22N2 | 278.399 | 2 / 0 | 3.9 | Yes |
| 40320 |  Aripiprazole | C23H27Cl2N3O2 | 448.388 | 4 / 1 | 4.6 | Yes |
| 43547 |  fluvoxamine | C15H21F3N2O2 | 318.34 | 7 / 1 | 2.6 | Yes |
| 44239 |  CHEMBL274767 | C22H27N3 | 333.479 | 2 / 2 | 4.6 | Yes |
| 44545 |  CHEMBL276031 | C19H26N2O | 298.43 | 2 / 1 | 3.9 | Yes |
| 45112 |  CHEMBL62429 | C19H30N2O3 | 334.46 | 4 / 2 | 3.9 | Yes |
| 47742 |  CHEMBL328866 | C23H26ClN3O3 | 427.929 | 4 / 2 | 3.2 | Yes |
| 52350 |  LR 5182 | C17H24Cl3N | 348.736 | 1 / 1 | N/A | N/A |
| 52694 |  CHEMBL1276948 | C23H25NO2 | 347.458 | 3 / 1 | 1.9 | Yes |
| 60385 |  CHEMBL536747 | C35H45F2N3 | 545.763 | 5 / 0 | 7.5 | No |
| 61830 |  CHEMBL331603 | C23H25ClN2O | 380.916 | 2 / 0 | 5.3 | No |
| 62210 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 66467 |  CHEMBL430798 | C19H18F3N3O4S | 441.425 | 9 / 0 | 3.2 | Yes |
| 67264 |  CHEMBL226124 | C34H44F2N4 | 546.751 | 6 / 0 | 6.4 | No |
| 68850 |  Azatadine M (nor), acetylated | C21H22N2O | 318.42 | 2 / 0 | 3.0 | Yes |
| 72239 |  CHEMBL60524 | C19H19ClN4O | 354.838 | 3 / 2 | 2.6 | Yes |
| 72891 |  CHEMBL11435 | C23H23ClN2O2 | 394.899 | 3 / 0 | 4.1 | Yes |
| 76351 |  ondansetron | C18H19N3O | 293.37 | 2 / 0 | 2.3 | Yes |
| 76923 |  methionine zwitterion | C5H11NO2S | 149.208 | 3 / 1 | -1.2 | Yes |
| 77024 |  DL-Homocysteine | C4H9NO2S | 135.181 | 4 / 3 | -3.4 | Yes |
| 81565 |  Sch-37370 | C21H21ClN2O | 352.862 | 2 / 0 | 4.4 | Yes |
| 83019 |  CHEMBL2111783 | C17H20FN3S | 317.426 | 4 / 0 | 2.6 | Yes |
| 83832 |  METIAMIDE | C9H16N4S2 | 244.375 | 3 / 3 | 0.5 | Yes |
| 86995 |  CHEMBL11313 | C23H25ClN2O2 | 396.915 | 3 / 1 | 3.9 | Yes |
| 87703 |  CHEMBL324336 | C19H20ClN3O | 341.839 | 3 / 0 | 2.6 | Yes |
| 88646 |  CHEMBL10903 | C22H23ClN2O2 | 382.888 | 3 / 0 | 4.7 | Yes |
| 93723 |  clomipramine | C19H23ClN2 | 314.857 | 2 / 0 | 5.2 | No |
| 94916 |  thiothixene | C23H29N3O2S2 | 443.624 | 6 / 0 | 3.8 | Yes |
| 95228 |  CHEMBL354210 | C23H29N3O | 363.505 | 3 / 1 | 3.3 | Yes |
| 99074 |  LY 344864 racemate | C21H22FN3O | 351.425 | 3 / 2 | 3.8 | Yes |
| 100427 |  dimethylhistaprodifen | C22H27N3 | 333.479 | 2 / 1 | 4.5 | Yes |
| 102333 |  CHEMBL1276947 | C25H27NO2 | 373.496 | 3 / 1 | 2.1 | Yes |
| 102922 |  CHEMBL516641 | C35H52O4 | 536.797 | 4 / 0 | 10.0 | No |
| 105638 |  Remoxipride | C16H23BrN2O3 | 371.275 | 4 / 1 | 2.1 | Yes |
| 108447 |  CHEMBL11136 | C22H23ClN2O2 | 382.888 | 3 / 0 | 4.4 | Yes |
| 109146 |  SERTINDOLE | C24H26ClFN4O | 440.947 | 3 / 1 | 4.1 | Yes |
| 110004 |  CHEMBL11515 | C22H27N3 | 333.479 | 2 / 2 | 4.4 | Yes |
| 111723 |  desipramine | C18H22N2 | 266.388 | 2 / 1 | 4.9 | Yes |
| 117366 |  CHEMBL334127 | C21H21ClN2O | 352.862 | 2 / 0 | 4.4 | Yes |
| 117647 |  CHEMBL11879 | C24H29N3 | 359.517 | 2 / 1 | 4.9 | Yes |
| 119418 |  methapyrilene | C14H19N3S | 261.387 | 4 / 0 | 2.6 | Yes |
| 119623 |  CHEMBL15986 | C23H28N2OS | 380.55 | 3 / 0 | 5.1 | No |
| 123625 |  METHDILAZINE | C18H20N2S | 296.432 | 3 / 0 | 5.2 | No |
| 125126 |  CHEMBL344942 | C21H21FN2O | 336.41 | 3 / 0 | 3.9 | Yes |
| 126049 |  CHEMBL15456 | C23H27Cl2N3OS | 464.449 | 4 / 0 | 5.4 | No |
| 126456 |  CHEMBL333455 | C18H22FN3S | 331.453 | 4 / 0 | 2.9 | Yes |
| 126577 |  BURIMAMIDE | C9H16N4S | 212.315 | 2 / 3 | 0.4 | Yes |
| 129865 |  CHEMBL325470 | C22H26ClN3O | 383.92 | 3 / 0 | 3.5 | Yes |
| 131036 |  CHEMBL264491 | C25H29N5 | 399.542 | 3 / 3 | 4.1 | Yes |
| 137131 |  CHEMBL11055 | C22H23ClN2O2 | 382.888 | 3 / 0 | 4.4 | Yes |
| 138538 |  CHEMBL275109 | C22H23ClN2O | 366.889 | 2 / 0 | 4.8 | Yes |
| 139941 |  CHEMBL1277312 | C22H23NO3 | 349.43 | 4 / 1 | 1.5 | Yes |
| 140628 |  Phenindamine | C19H19N | 261.368 | 1 / 0 | 3.1 | Yes |
| 141110 |  CHEMBL558789 | C35H49ClFN3O | 582.245 | 5 / 1 | N/A | No |
| 142852 |  CHEMBL280063 | C21H23Cl2N3OS | 436.395 | 4 / 0 | 4.7 | Yes |
| 147152 |  CHEMBL418653 | C20H23N5O | 349.438 | 4 / 2 | 1.7 | Yes |
| 147154 |  CHEMBL226227 | C35H47FN4 | 542.787 | 5 / 0 | 6.7 | No |
| 147284 |  loratadine | C22H23ClN2O2 | 382.888 | 3 / 0 | 5.2 | No |
| 147854 |  CHEMBL415985 | C21H24N2OS | 352.496 | 3 / 0 | 4.5 | Yes |
| 149705 |  CHEMBL367045 | C17H19N3S | 297.42 | 3 / 0 | 3.0 | Yes |
| 150287 |  CHEMBL366388 | C24H29FN2O | 380.507 | 4 / 0 | 4.1 | Yes |
| 150461 |  adiphenine | C20H25NO2 | 311.425 | 3 / 0 | 4.2 | Yes |
| 151176 |  CHEMBL124466 | C20H21ClN2O | 340.851 | 2 / 0 | 3.5 | Yes |
| 151178 |  CHEMBL141432 | C20H21ClN2O | 340.851 | 2 / 0 | 3.5 | Yes |
| 152221 |  CYPROHEPTADINE | C21H21N | 287.406 | 1 / 0 | 4.7 | Yes |
| 152772 |  CHEMBL15499 | C16H23N3OS | 305.44 | 4 / 1 | 2.5 | Yes |
| 154591 |  CHEMBL139760 | C21H20Cl2N2O | 387.304 | 2 / 0 | 5.1 | No |
| 154894 |  CHEMBL342455 | C24H27ClN2O | 394.943 | 2 / 0 | 5.8 | No |
| 155056 |  CHEMBL303334 | C15H20Br2N2O3 | 436.144 | 4 / 2 | 3.0 | Yes |
| 158689 |  CHEMBL60961 | C20H23ClN4 | 354.882 | 3 / 2 | 3.4 | Yes |
| 169698 |  CHEMBL15955 | C21H25N3OS | 367.511 | 4 / 0 | 3.6 | Yes |
| 170570 |  Pyrathiazine | C18H20N2S | 296.432 | 3 / 0 | 4.7 | Yes |
| 171800 |  thioridazine | C21H26N2S2 | 370.573 | 4 / 0 | 5.9 | No |
| 174882 |  methysergide | C21H27N3O2 | 353.466 | 3 / 2 | 2.3 | Yes |
| 176434 |  amitriptyline | C20H23N | 277.411 | 1 / 0 | 5.0 | Yes |
| 178705 |  CHEMBL46683 | C22H22FN3O4 | 411.433 | 6 / 2 | 2.2 | Yes |
| 562968 |  olanzapine | C17H20N4S | 312.435 | 4 / 1 | 2.9 | Yes |
| 180393 |  Benzamil | C13H14ClN7O | 319.753 | 6 / 4 | 1.7 | Yes |
| 183186 |  CHEMBL117406 | C18H20ClN3 | 313.829 | 3 / 1 | 2.7 | Yes |
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