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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	fluvoxamine
Molecular formula	C15H21F3N2O2
IUPAC name	2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethanamine
Molecular weight	318.34
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.6
Synonyms	NCGC00018193-04 O4L1XPO44W 1-Pentanone, 5-methoxy-1-(4-(trifluoromethyl)phenyl)-, O-(2-aminoethyl)oxime, (E)- ZINC12466082 917096-37-8 AC1Q4JNU BPBio1_001199 CHEBI:5138 DSSTox_RID_80097 I01-8382 NCGC00018193-07 (1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one O-(2-aminoethyl)oxime Prestwick3_000995 39F183 AB00513735_05 AS-15332 C07571 CS-1840 Dumyrox fluvoxamine-CR LS-101999 NCGC00021870-04 (E)-5-Methoxy-1-(4-(trifluoromethyl)phenyl)pentan-1-one O-(2-aminoethyl)oxime Tox21_110837_1 54739-18-3 AC-1679 BDBM50028091 CC-28527 DSSTox_CID_24002 Fluvoxamina FVX Maveral NCGC00018193-05 O893 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethanamine A830353 AKOS016003882 BRD-K53517854-050-03-2 DTXSID2044002 Fluvoxamine (INN) KB-209259 NCGC00018193-08 (2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine SCHEMBL33983 5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone O-(2-aminoethyl)oxime AB00513735_06 AX8021384 C15H21F3N2O2 D03HFG Faverin Fluvoxaminum Luvox (TN) NCGC00021870-05 (E)-5-Methoxy-4'-(trifluormethyl)valerophenon-O-(2-aminoethyl)oxim UNII-O4L1XPO44W 61718-82-9 (maleate) AC1NT50J BIDD:GT0609 CCG-204586 DSSTox_GSID_44002 Fluvoxamina [INN-Spanish] HY-B0103 MolPort-005-943-374 NCGC00018193-06 Prestwick2_000995 2-[({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino)oxy]ethanamine AB0016707 AN-5830 BSPBio_001089 CHEMBL814 Dumirox Fluvoxamine [INN:BAN] Lopac0_000495 NCGC00018193-11 (E)-5-Methoxy-1-(4-(trifluoromethyl)phenyl)-pentan-1-one O-(2-aminoethyl) oxime Tox21_110837 AB00514702 BC226180 CAS-54739-18-3 D07984 Floxyfral Fluvoxaminum [INN-Latin] Luvox, Floxyfral [ Show all ]
Inchi Key	CJOFXWAVKWHTFT-XSFVSMFZSA-N
Inchi ID	InChI=1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18/h5-8H,2-4,9-11,19H2,1H3/b20-14+
PubChem CID	5324346
ChEMBL	CHEMBL814
IUPHAR	N/A
BindingDB	50028091
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
43546	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
555643	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
43554	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
43553	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
555644	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
43550	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
459604	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
43548	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
43551	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
555645	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
43547	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
43552	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
43555	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
43549	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466

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