You can:
| Name | Alpha-2C adrenergic receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Adra2c |
| Synonym | alpha2C-adrenoceptor alpha2-C4 Alpha-2CAR alpha-2C adrenoreceptor Alpha-2C adrenoceptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 458 |
| Amino acid sequence | MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRRGGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ |
| UniProt | P22086 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL314 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 89 |  Eticlopride | C17H25ClN2O3 | 340.848 | 4 / 2 | 3.1 | Yes |
| 5772 |  paroxetine | C19H20FNO3 | 329.371 | 5 / 1 | 3.5 | Yes |
| 8203 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 10524 |  CHEMBL30739 | C13H16N2S | 232.345 | 2 / 1 | 3.2 | Yes |
| 11730 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 13696 |  BDBM86280 | C17H18BrNO2 | 348.24 | 3 / 3 | 3.2 | Yes |
| 16769 |  Pipamperone | C21H30FN3O2 | 375.488 | 5 / 1 | 2.0 | Yes |
| 16987 |  Metrenperone | C24H26FN3O2 | 407.489 | 5 / 0 | 2.7 | Yes |
| 20170 |  imipramine | C19H24N2 | 280.415 | 2 / 0 | 4.8 | Yes |
| 21865 |  OPC-28326 | C26H35N3O2 | 421.585 | 3 / 1 | 4.3 | Yes |
| 22602 |  CHEMBL284213 | C11H12N2S | 204.291 | 2 / 1 | 2.3 | Yes |
| 23226 |  CHEMBL43345 | C17H17NO2 | 267.328 | 3 / 3 | 2.5 | Yes |
| 23350 |  sulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 26556 |  Rauwolscine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26578 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 30163 |  Metopimazine | C22H27N3O3S2 | 445.596 | 6 / 1 | 3.1 | Yes |
| 35776 |  CHEMBL286269 | C11H12N2S | 204.291 | 2 / 1 | 2.5 | Yes |
| 38110 |  Reboxetine | C19H23NO3 | 313.397 | 4 / 1 | 3.0 | Yes |
| 43550 |  fluvoxamine | C15H21F3N2O2 | 318.34 | 7 / 1 | 2.6 | Yes |
| 44540 |  CHEMBL276031 | C19H26N2O | 298.43 | 2 / 1 | 3.9 | Yes |
| 45110 |  CHEMBL62429 | C19H30N2O3 | 334.46 | 4 / 2 | 3.9 | Yes |
| 50747 |  levomedetomidine | C13H16N2 | 200.285 | 1 / 1 | 3.1 | Yes |
| 52349 |  LR 5182 | C17H24Cl3N | 348.736 | 1 / 1 | N/A | N/A |
| 60321 |  Talipexole | C10H15N3S | 209.311 | 4 / 1 | 1.5 | Yes |
| 62221 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 83877 |  Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
| 86842 |  BDBM86273 | C18H17BrF3NO2 | 416.238 | 6 / 2 | 4.6 | Yes |
| 93740 |  clomipramine | C19H23ClN2 | 314.857 | 2 / 0 | 5.2 | No |
| 94903 |  thiothixene | C23H29N3O2S2 | 443.624 | 6 / 0 | 3.8 | Yes |
| 96862 |  Skf-81297 | C16H16ClNO2 | 289.759 | 3 / 3 | 2.7 | Yes |
| 98249 |  clonidine | C9H9Cl2N3 | 230.092 | 1 / 2 | 1.6 | Yes |
| 99071 |  LY 344864 racemate | C21H22FN3O | 351.425 | 3 / 2 | 3.8 | Yes |
| 101549 |  SCH 23390 | C17H18ClNO | 287.787 | 2 / 1 | 4.0 | Yes |
| 105643 |  Remoxipride | C16H23BrN2O3 | 371.275 | 4 / 1 | 2.1 | Yes |
| 109144 |  SERTINDOLE | C24H26ClFN4O | 440.947 | 3 / 1 | 4.1 | Yes |
| 111731 |  desipramine | C18H22N2 | 266.388 | 2 / 1 | 4.9 | Yes |
| 112189 |  zotepine | C18H18ClNOS | 331.858 | 3 / 0 | 4.8 | Yes |
| 114385 |  BDBM86270 | C17H18BrNO2 | 348.24 | 3 / 3 | 3.2 | Yes |
| 116898 |  Skf-82958 | C19H20ClNO2 | 329.824 | 3 / 2 | 3.9 | Yes |
| 118077 |  SKF 83822 | C20H22ClNO2 | 343.851 | 3 / 2 | 4.2 | Yes |
| 120813 |  IDAZOXAN | C11H12N2O2 | 204.229 | 3 / 1 | 0.7 | Yes |
| 125084 |  Rec 15/3079 | C26H34N4O4 | 466.582 | 6 / 0 | 4.8 | Yes |
| 126063 |  Pirenperone | C23H24FN3O2 | 393.462 | 5 / 0 | 2.6 | Yes |
| 131345 |  prazosin | C19H21N5O4 | 383.408 | 8 / 1 | 2.0 | Yes |
| 134737 |  QUIPAZINE,8-Me | C14H17N3 | 227.311 | 3 / 1 | 2.4 | Yes |
| 137326 |  GUANFACINE | C9H9Cl2N3O | 246.091 | 1 / 2 | 2.0 | Yes |
| 140183 |  BDBM86710 | C27H33BrF3N3O3 | 584.478 | 8 / 0 | 6.8 | No |
| 151996 |  tolazoline | C10H12N2 | 160.22 | 1 / 1 | 2.6 | Yes |
| 155060 |  CHEMBL303334 | C15H20Br2N2O3 | 436.144 | 4 / 2 | 3.0 | Yes |
| 160039 |  SKF 38393 | C16H17NO2 | 255.317 | 3 / 3 | 2.5 | Yes |
| 160348 |  ritanserin | C27H25F2N3OS | 477.574 | 6 / 0 | 5.2 | No |
| 160837 |  Spiroxatrine | C22H25N3O3 | 379.46 | 5 / 1 | 3.1 | Yes |
| 162489 |  UNII-39YLC3L0ZU | C18H20ClNO2 | 317.813 | 3 / 2 | 3.6 | Yes |
| 162493 |  Skf-83959 | C18H20ClNO2 | 317.813 | 3 / 2 | 3.6 | Yes |
| 162671 |  BDBM86274 | C17H15BrF3NO2 | 402.211 | 6 / 3 | 3.7 | Yes |
| 162831 |  INDORAMIN | C22H25N3O | 347.462 | 2 / 2 | 4.1 | Yes |
| 164742 |  BDBM86275 | C18H20BrNO2 | 362.267 | 3 / 2 | 4.1 | Yes |
| 171767 |  thioridazine | C21H26N2S2 | 370.573 | 4 / 0 | 5.9 | No |
| 176441 |  amitriptyline | C20H23N | 277.411 | 1 / 0 | 5.0 | Yes |
| 180147 |  AMPHETAMINE | C9H13N | 135.21 | 1 / 1 | 1.8 | Yes |
| 180383 |  Benzamil | C13H14ClN7O | 319.753 | 6 / 4 | 1.7 | Yes |
| 183256 |  BDBM86264 | C18H20BrNO2 | 362.267 | 3 / 2 | 4.1 | Yes |
| 189739 |  BDBM86265 | C20H22BrNO2 | 388.305 | 3 / 2 | 4.7 | Yes |
| 191531 |  haloperidol | C21H23ClFNO2 | 375.868 | 4 / 1 | 3.2 | Yes |
| 196382 |  periciazine | C21H23N3OS | 365.495 | 5 / 1 | 3.5 | Yes |
| 199417 |  Piperoxan | C14H19NO2 | 233.311 | 3 / 0 | 2.6 | Yes |
| 201796 |  SK&F-104078 | C16H22ClNO | 279.808 | 2 / 0 | 4.4 | Yes |
| 208232 |  Butanserin | C24H26FN3O3 | 423.488 | 5 / 1 | 3.3 | Yes |
| 210307 |  BDBM86281 | C20H22BrNO2 | 388.305 | 3 / 2 | 4.7 | Yes |
| 210872 |  GR 113808 | C19H27N3O4S | 393.502 | 6 / 1 | 1.7 | Yes |
| 212014 |  Robalzotan BNAD 299 HCL | C18H23FN2O2 | 318.392 | 4 / 1 | 2.8 | Yes |
| 212196 |  AC1NKXXY | C17H19N3O | 281.359 | 2 / 2 | 3.3 | Yes |
| 215516 |  Ziprasidone | C21H21ClN4OS | 412.936 | 5 / 1 | 4.0 | Yes |
| 218809 |  Vanoxerine | C28H32F2N2O | 450.574 | 5 / 0 | 5.6 | No |
| 224931 |  (E)-Flupenthixol | C23H25F3N2OS | 434.521 | 7 / 1 | 4.5 | Yes |
| 227462 |  Amperozide | C23H29F2N3O | 401.502 | 4 / 1 | 4.1 | Yes |
| 231616 |  amisulpride | C17H27N3O4S | 369.48 | 6 / 2 | 1.5 | Yes |
| 241974 |  GTP gamma-4-azidoanilide | C16H20N9O13P3 | 639.307 | 18 / 8 | -1.9 | No |
| 247635 |  piribedil | C16H18N4O2 | 298.346 | 6 / 0 | 1.8 | Yes |
| 249108 |  D0V8NS | C25H30N2O3 | 406.526 | 5 / 0 | 4.2 | Yes |
| 259704 |  BDBM86272 | C20H19BrF3NO2 | 442.276 | 6 / 2 | 5.2 | No |
| 260099 |  Dothiepin | C19H21NS | 295.444 | 2 / 0 | 4.5 | Yes |
| 263180 |  Flufylline | C21H24FN5O3 | 413.453 | 6 / 0 | 1.5 | Yes |
| 263730 |  Paliperidone | C23H27FN4O3 | 426.492 | 7 / 1 | 2.2 | Yes |
| 264422 |  venlafaxine | C17H27NO2 | 277.408 | 3 / 1 | 2.9 | Yes |
| 270403 |  Fla-797 | C15H21BrN2O3 | 357.248 | 4 / 2 | 2.3 | Yes |
| 273566 |  CHEMBL1203852 | C8H8BrClN2S | 279.58 | 2 / 2 | N/A | N/A |
| 273747 |  Benoxathian | C19H23NO4S | 361.456 | 6 / 1 | 3.4 | Yes |
| 274468 |  Skf-77434 | C19H21NO2 | 295.382 | 3 / 2 | 3.6 | Yes |
| 275104 |  CHEMBL1193219 | C17H18ClNO2 | 303.786 | 3 / 3 | 3.1 | Yes |
| 280260 |  Thioperamide | C15H24N4S | 292.445 | 2 / 2 | 2.4 | Yes |
| 283494 |  Fluspirilene | C29H31F2N3O | 475.584 | 5 / 1 | 5.6 | No |
| 284461 |  SCHEMBL6933222 | C27H37N3O3 | 451.611 | 5 / 0 | 4.9 | Yes |
| 290321 |  serotonin | C10H12N2O | 176.219 | 2 / 3 | 0.2 | Yes |
| 291507 |  risperidone | C23H27FN4O2 | 410.493 | 6 / 0 | 2.7 | Yes |
| 292023 |  Setoperone | C21H24FN3O2S | 401.5 | 6 / 0 | 2.8 | Yes |
| 299091 |  CHEMBL284795 | C13H14N2S | 230.329 | 2 / 1 | 2.8 | Yes |
| 300680 |  CHEMBL524153 | C28H32N4O4 | 488.588 | 7 / 1 | 3.7 | Yes |
| 301171 |  BCTC | C20H25ClN4O | 372.897 | 3 / 1 | 4.3 | Yes |
| 301324 |  mirtazapine | C17H19N3 | 265.36 | 3 / 0 | 3.3 | Yes |
zhanglab
zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417