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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Amperozide
Molecular formula	C23H29F2N3O
IUPAC name	4-[4,4-bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxamide
Molecular weight	401.502
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.1
Synonyms	4-(4,4-Bis(p-fluorophenyl)butyl)-N-ethyl-1-piperazinecarboxamide Amperozida [INN-Spanish] BRD-K52397688-001-01-9 DB08927 LS-177195 UNII-0M2W3TAG39 75558-90-6 Amperozide [INN:BAN] CHEBI:92913 FG-5606 NCGC00015081-03 1-Piperazinecarboxamide, 4-(4,4-bis(p-fluorophenyl)butyl)-N-ethyl- AKOS030548015 API0008640 D0V4JO Lopac-A-6976 PDSP2_000730 C23H29F2N3O DTXSID6048416 NCGC00015081-01 ZINC4214849 AC1L2JOA Amperozidum Hogpax vet. NCGC00162051-01 4-(4,4-Bis(4-fluorphenyl)butyl)-N-ethyl-1-piperazinecarboxamid Amperozida BDBM50311786 Lopac0_000040 SCHEMBL340961 75529-73-6 (hydrochloride) Amperozide [BAN:INN] CCG-204136 FG 5606 NCGC00015081-02 0M2W3TAG39 AC1Q4NM7 Amperozidum [INN-Latin] CHEMBL1079935 L000997 PDSP1_000742 [ Show all ]
Inchi Key	NNAIYOXJNVGUOM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H29F2N3O/c1-2-26-23(29)28-16-14-27(15-17-28)13-3-4-22(18-5-9-20(24)10-6-18)19-7-11-21(25)12-8-19/h5-12,22H,2-4,13-17H2,1H3,(H,26,29)
PubChem CID	73333
ChEMBL	CHEMBL1079935
IUPHAR	N/A
BindingDB	50311786
DrugBank	DB08927
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
227455	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
556369	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
227453	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
227454	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
227461	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
556370	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
227457	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
227462	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
227452	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
227456	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
556371	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
227458	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
227451	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
227460	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
227459	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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