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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	OPC-28326
Molecular formula	C26H35N3O2
IUPAC name	N-[2,6-dimethyl-4-[4-[methyl(2-phenylethyl)amino]piperidine-1-carbonyl]phenyl]propanamide
Molecular weight	421.585
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.3
Synonyms	N-[2,6-dimethyl-4-[4-[methyl(phenethyl)amino]piperidine-1-carbonyl]phenyl]propanamide BDBM85825 PDSP1_000826 HY-101610 ZINC3985553 NSC_219019 CAS_219019 PDSP2_000813 L001587 AC1L55WP CS-6725 SCHEMBL2831451 [ Show all ]
Inchi Key	BESKMDLUOAVUJF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H35N3O2/c1-5-24(30)27-25-19(2)17-22(18-20(25)3)26(31)29-15-12-23(13-16-29)28(4)14-11-21-9-7-6-8-10-21/h6-10,17-18,23H,5,11-16H2,1-4H3,(H,27,30)
PubChem CID	219020
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85825
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21864	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
21865	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458

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