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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Metopimazine
Molecular formula	C22H27N3O3S2
IUPAC name	1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide
Molecular weight	445.596
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.1
Synonyms	BRN 4278585 DTXSID80161224 Metopimazina Nortrip US9132134, Metopimazine (NG101) 1-[3-[2-(Methylsulfonyl)-10H-phenothiazin-10-yl]propyl]piperidin-4-carboxamide 238S75V9AV AN-17207 CHEBI:135726 EXP-999 Metopimazine (USAN/INN) RP 9965 1-(3-(2-(Methylsulfonyl)phenothiazin-10-yl)propyl)isonipecotamide 118285-EP2275420A1 14008-44-7 4-Piperidinecarboxamide, 1-[3-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]propyl]- BDBM82383 CTK8E9457 J-007351 Metopimazinum TX-013443 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide 2-Methylsulfonyl-10-(3-(4-carbamoylpiperidino)propyl)phenothiazine AC1L1B19 C22H27N3O3S2 EINECS 237-818-4 Metopimazina [INN-Spanish] NSC_26388 Vogalene 1-(3-(2-(Methylsulfonyl)-10H-phenothiazin-10-yl)propyl)-4-piperidinecarboxamide 1-[3-[2-(Methylsulfonyl)phenothiazin-10-yl]propyl]isonipecotamide 4-Piperidinecarboxamide, 1-(3-(2-(methanesulfonyl)phenothiazin-10-yl)propyl)- BCP9000921 FT-0672379 Metopimazine [USAN:BAN:INN] RP-9965 1-(3-(2-methylsulfonylphenothiazin-10-yl) propyl)isonipecotinamide 118285-EP2298764A1 14170-03-7 4-Piperidinecarboxamide,1-[3-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]propyl]- BQDBKDMTIJBJLA-UHFFFAOYSA-N D05010 LS-85054 Metopimazinum [INN-Latin] UNII-238S75V9AV 1-[3-[2-(Methylsulfonyl)-10H-phenothiazin-10-yl]propyl]-4-piperidinecarboxamide 2-Methylsulfonyl-10-[3-(4-carbamoylpiperidino)propyl]phenothiazine AKOS005065914 CAS_26388 EXP 999 Phenothiazine, 10-(3-(4'-carbamoylpiperidino)propyl)-2-methylsulfonyl- ZINC537996 1-(3-(2-(Methylsulfonyl)phenothiazin-10-yl)propyl)-4-piperidinecarboxamide 10-(3-(4-Carbamoylpiperidine)propyl)-2-(methanesulfonyl)phenothiazine 118285-EP2298765A1 4-Piperidinecarboxamide, 1-(3-(2-(methylsulfonyl)-10H-phenothiazin-10-yl)propyl)- BDBM179867 CHEMBL398615 ISONIPECOTAMIDE, 1-(3-(2-(METHYLSULFONYL)PHENOTHIAZIN-10-YL)PROPYL)- Metopimazine [USAN:INN:BAN] SCHEMBL49905 1-(3-[2-(Methylsulfonyl)-10H-phenothiazin-10-yl]propyl)-4-piperidinecarboxamide # [ Show all ]
Inchi Key	BQDBKDMTIJBJLA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27N3O3S2/c1-30(27,28)17-7-8-21-19(15-17)25(18-5-2-3-6-20(18)29-21)12-4-11-24-13-9-16(10-14-24)22(23)26/h2-3,5-8,15-16H,4,9-14H2,1H3,(H2,23,26)
PubChem CID	26388
ChEMBL	CHEMBL398615
IUPHAR	N/A
BindingDB	179867, 82383
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
30162	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
30163	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
459474	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
459472	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
459473	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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