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Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
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Ligand

Name	Fluspirilene
Molecular formula	C29H31F2N3O
IUPAC name	8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight	475.584
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.6
Synonyms	8-[4,4-bis(4-fluorophenyl)butyl]-4-phenyl-2,4,8-triazaspiro[4.5]decan-1-one NCGC00015424-05 AOB33780 NCGC00093913-02 BSPBio_000752 Prestwick2_000906 CHEMBL46516 SMR000058304 DSSTox_CID_25152 Tox21_110142_1 Fluspiriline HMS2233B20 J-011797 1841-19-6 MFCD00055137 MolPort-002-540-769 AB00513956 NCGC00015424-08 BCP09254 NCGC00093913-05 C5QA4GLR9M R 6218 CTK7B9885 spiropiperidine analogue, 1 DTXSID7045152 ZINC537755 Fluspirilene, European Pharmacopoeia (EP) Reference Standard HMS1570F14 HMS3402D05 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4,4-bis(p-fluorophenyl)butyl)-1-phenyl- Lopac0_000518 8-(4,4-Bis(p-fluorophenyl)butyl)-1-phenyl-1,3,8-triazaspiro(4,5)decan-4-one 8-[4,4-bis (p-fluorophenyl)butyl]-1-phenyl-1,3,8-triazino[4,5]decan-4-one NCGC00015424-03 ACM1841196 NCGC00016595-01 BRD-K77947974-001-04-9 Prestwick0_000906 CHEBI:93369 Redeptin SR-01000075385-5 F-100 Fluspirilenum HMS2089C15 Imap 1,3,8-Triazaspiro[4.5]decan-4-one,8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl- McN-JR 6218 MLS000069357 8-[4,4-bis(p-Fluorophenyl)butyl]-1-phenyl-1,3,8-triazino[4.5]decan-4-one NCGC00015424-06 API0008485 NCGC00093913-03 BSPBio_001343 Prestwick3_000906 cid_3396 SPBio_002951 DSSTox_GSID_45152 Tox21_500518 Fluspirilene (USAN/INN) FT-0668770 HMS3261H17 L001195 NCGC00015424-01 AB00513956-10 NCGC00015424-09 BDBM26948 NCGC00261203-01 CAS-1841-19-6 R-6218 D02629 SR-01000075385 EINECS 217-418-6 Fluspirileno HMS1791D05 HMS3714F14 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl- LP00518 8-(4,4-Bis(p-fluorophenyl)butyl)-1-phenyl-1,3,8-triazaspiro-(4.5)decan-4-one 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one NCGC00015424-04 AKOS015969747 NCGC00093913-01 BRN 0633853 Prestwick1_000906 SCHEMBL42082 DB04842 Tox21_110142 Fluspirilen Fluspirilenum [INN-Latin] HMS2097F14 Imap (TN) 1-Phenyl-4-oxo-8-(4,4-bis(4-fluorophenyl)butyl)-1,3,8-triazaspiro(4,5)decane McN-JR-6218 MLS001333730 NCGC00015424-07 AS-16749 NCGC00093913-04 C29H31F2N3O QOYHHIBFXOOADH-UHFFFAOYSA-N CS-0013609 Spirodiflamine DSSTox_RID_80706 UNII-C5QA4GLR9M Fluspirilene [USAN:INN:BAN] GTPL85 HMS3372H20 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4,4-bis(4-fluorophenyl)butyl)-1-phenyl- Lopac-F-100 5-26-04-00097 (Beilstein Handbook Reference) 8-[4,4-bis (p-fluorophenyl)butyl]- 1-phenyl-1,3,8-triazino[4,5]decan-4-one NCGC00015424-02 AC1L1FUB NCGC00015424-11 BPBio1_000828 Oprea1_804941 CCG-204608 R6218 D0U5FS SR-01000075385-1 EU-0100518 Fluspirileno [INN-Spanish] HMS1989D05 HY-B1655 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[4,4-bis(p-fluorophenyl)butyl]-1-phenyl- LS-154759 [ Show all ]
Inchi Key	QOYHHIBFXOOADH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35)
PubChem CID	3396
ChEMBL	CHEMBL46516
IUPHAR	85
BindingDB	26948
DrugBank	DB04842
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
283479	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
283484	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
283470	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
283483	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
283466	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
283489	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
283467	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
556574	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
283492	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
283485	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
283493	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
283482	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
283469	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
283487	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
283494	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
283476	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
283474	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
283486	Cysteinyl leukotriene receptor 1	Q2NNR5	CYSLTR1	Cavia porcellus (Guinea pig)	340
283464	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
283478	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446

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