You can:
| Name | 5-hydroxytryptamine receptor 1E |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | HTR1E |
| Synonym | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 5-HT1Ealpha 5-ht1e receptor 5-HT1E 5-HT-1E [ Show all ] |
| Disease | N/A |
| Length | 365 |
| Amino acid sequence | MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT |
| UniProt | P28566 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P28566 |
| 3D structure model | This predicted structure model is from GPCR-EXP P28566. |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2182 |
| IUPHAR | 4 |
| DrugBank | BE0000476 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 35 |  MLS000077136 | C12H11N3O6 | 293.235 | 8 / 1 | -0.1 | Yes |
| 1032 |  CHEMBL2205816 | C18H20N2O | 280.371 | 3 / 1 | 1.8 | Yes |
| 553250 |  7-Hydroxy Risperidone | C23H27FN4O3 | 426.492 | 7 / 1 | 1.7 | Yes |
| 1469 |  4365 CT | C14H20N2O | 232.327 | 2 / 1 | 2.7 | Yes |
| 2258 |  1-(cyclohexylmethyl)pyrrolidine | C11H21N | 167.296 | 1 / 0 | 3.1 | Yes |
| 5251 |  SB-258719 | C18H30N2O2S | 338.51 | 4 / 0 | 3.5 | Yes |
| 5680 |  AC1L1HUK | C29H28ClN3O4 | 518.01 | 4 / 2 | 5.2 | No |
| 6273 |  CHEMBL76237 | C19H22N2O3S | 358.456 | 4 / 0 | 3.5 | Yes |
| 463732 |  CHEMBL3633757 | C26H24BrNO4 | 494.385 | 5 / 0 | 5.4 | No |
| 536122 |  CHEMBL3899832 | C22H19N5O4 | 417.425 | 8 / 2 | 3.6 | Yes |
| 8196 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 521696 |  CHEMBL3754496 | C16H19FN2 | 258.34 | 2 / 1 | 2.9 | Yes |
| 553291 |  naratriptan | C17H25N3O2S | 335.466 | 4 / 2 | 2.0 | Yes |
| 10439 |  SB 204070 hydrochloride | C19H27ClN2O4 | 382.885 | 6 / 1 | 3.5 | Yes |
| 10736 |  CHEMBL3287723 | C25H32O7 | 444.524 | 7 / 2 | 5.7 | No |
| 11068 |  tryptamine | C10H12N2 | 160.22 | 1 / 2 | 1.6 | Yes |
| 11893 |  MLS000090902 | C19H21NO4 | 327.38 | 4 / 1 | 2.6 | Yes |
| 13671 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 14227 |  180083-23-2 | C32H32N4O3 | 520.633 | 6 / 0 | 5.6 | No |
| 14858 |  TCMDC-124447 | C15H18N2 | 226.323 | 1 / 1 | 2.6 | Yes |
| 15481 |  CHEMBL2205829 | C19H19NO3 | 309.365 | 4 / 1 | 2.2 | Yes |
| 16793 |  Pipamperone | C21H30FN3O2 | 375.488 | 5 / 1 | 2.0 | Yes |
| 18188 |  MLS000583267 | C23H22N2O4 | 390.439 | 5 / 1 | 5.5 | No |
| 21147 |  SCHEMBL3825498 | C23H32N2O2S | 400.581 | 4 / 0 | 4.9 | Yes |
| 21154 |  CHEMBL114012 | C23H32N2O2S | 400.581 | 4 / 0 | 4.9 | Yes |
| 22551 |  CHEMBL283036 | C19H19F3N4 | 360.384 | 6 / 1 | 3.6 | Yes |
| 23175 |  1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | C11H16INO2 | 321.158 | 3 / 1 | 2.5 | Yes |
| 24283 |  CHEMBL2181168 | C21H24IN3O | 461.347 | 4 / 0 | 5.1 | No |
| 24806 |  lysergol | C16H18N2O | 254.333 | 2 / 2 | 2.2 | Yes |
| 24815 |  Lysergole | C16H18N2O | 254.333 | 2 / 2 | 2.2 | Yes |
| 536624 |  2-Chloroadenosine | C10H12ClN5O4 | 301.687 | 8 / 4 | -0.1 | Yes |
| 26288 |  CHEMBL600053 | C18H18FNO | 283.346 | 3 / 1 | 2.5 | Yes |
| 553394 |  Rauwolscine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26583 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26631 |  CHEBI:48565 | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 27038 |  SB-357134 | C17H18Br2FN3O3S | 523.215 | 7 / 2 | 3.4 | No |
| 27514 |  CHEMBL2432063 | C19H29N | 271.448 | 1 / 0 | 4.7 | Yes |
| 30197 |  SCHEMBL14542291 | C22H21NO3 | 347.414 | 3 / 0 | 4.3 | Yes |
| 548237 |  CHEMBL3959210 | C14H18ClN5O3 | 339.78 | 7 / 3 | 0.3 | Yes |
| 33038 |  memantine | C12H21N | 179.307 | 1 / 1 | 3.3 | Yes |
| 40314 |  Aripiprazole | C23H27Cl2N3O2 | 448.388 | 4 / 1 | 4.6 | Yes |
| 40845 |  MLS000058422 | C15H19ClN2O3 | 310.778 | 4 / 1 | 3.4 | Yes |
| 41082 |  CHEMBL476838 | C23H29FN2O5 | 432.492 | 7 / 1 | 3.9 | Yes |
| 42476 |  CHEMBL2432039 | C20H23N | 277.411 | 1 / 1 | 2.7 | Yes |
| 42929 |  3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | C13H14N2 | 198.269 | 1 / 2 | 1.8 | Yes |
| 44000 |  CHEMBL2432060 | C21H26FN | 311.444 | 2 / 0 | 4.8 | Yes |
| 45785 |  23981-80-8 | C14H14O3 | 230.263 | 3 / 1 | 3.3 | Yes |
| 46984 |  CHEMBL277452 | C34H40N6O2 | 564.734 | 4 / 6 | 3.6 | No |
| 47480 |  CHEMBL2432051 | C21H27NO3 | 341.451 | 4 / 1 | 3.3 | Yes |
| 52557 |  CHEMBL590615 | C19H20FNO | 297.373 | 3 / 1 | 3.0 | Yes |
| 469515 |  CHEMBL3609143 | C29H29NO4 | 455.554 | 5 / 0 | 5.4 | No |
| 53806 |  {4-[(3-fluorophenyl)methoxy]phenyl}methanamine hydrochloride | C14H15ClFNO | 267.728 | 3 / 2 | N/A | N/A |
| 469625 |  CHEMBL3608451 | C27H27NO4 | 429.516 | 5 / 0 | 5.1 | No |
| 55651 |  fenfluramine | C12H16F3N | 231.262 | 4 / 1 | 3.4 | Yes |
| 56294 |  MLS000861141 | C19H15N3O3 | 333.347 | 5 / 0 | 4.0 | Yes |
| 56326 |  CHEMBL2205833 | C17H18N2O | 266.344 | 3 / 1 | 1.3 | Yes |
| 57040 |  SMR000078951 | C21H22N2O3 | 350.418 | 3 / 0 | 3.6 | Yes |
| 548538 |  Aripiprazole lauroxil | C36H51Cl2N3O4 | 660.721 | 6 / 0 | 10.0 | No |
| 523215 |  CHEMBL3770342 | C14H18BrN5 | 336.237 | 2 / 3 | 2.3 | Yes |
| 57979 |  CHEMBL2432053 | C19H22N2O | 294.398 | 3 / 0 | 2.0 | Yes |
| 60050 |  MLS000048662 | C18H27N4O3P | 378.413 | 6 / 0 | 1.5 | Yes |
| 60506 |  CHEMBL253597 | C21H20N2O3 | 347.402 | 4 / 0 | 3.2 | Yes |
| 62202 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 62524 |  SMR000025686 | C23H24ClN3O3 | 425.913 | 4 / 2 | 4.3 | Yes |
| 63178 |  phenylpropanolamine | C9H13NO | 151.209 | 2 / 2 | 0.8 | Yes |
| 63577 |  MLS000033110 | C12H11N5O2S | 289.313 | 4 / 0 | 1.4 | Yes |
| 69031 |  methylphenidate | C14H19NO2 | 233.311 | 3 / 1 | 0.2 | Yes |
| 69149 |  CHEMBL137781 | C21H25N3O | 335.451 | 2 / 1 | 3.2 | Yes |
| 69176 |  CHEMBL343755 | C21H25N3O | 335.451 | 2 / 1 | 3.2 | Yes |
| 69189 |  CHEMBL138989 | C21H25N3O | 335.451 | 2 / 1 | 3.2 | Yes |
| 69641 |  CHEMBL2432049 | C18H22N2 | 266.388 | 2 / 1 | 2.8 | Yes |
| 69699 |  CHEMBL282971 | C23H26ClN3O3S2 | 492.049 | 7 / 1 | 5.2 | No |
| 69709 |  CHEMBL29433 | C23H26ClN3O3S2 | 492.049 | 7 / 1 | 5.2 | No |
| 70205 |  CHEMBL3104091 | C20H20N2 | 288.394 | 1 / 0 | 3.9 | Yes |
| 70906 |  CHEMBL1651208 | C27H24ClNO4 | 461.942 | 4 / 1 | 5.5 | No |
| 72088 |  MLS000044646 | C10H7F3N2O3S | 292.232 | 8 / 0 | 1.5 | Yes |
| 73159 |  CHEMBL1258452 | C18H28N2O3 | 320.433 | 5 / 1 | 3.1 | Yes |
| 73736 |  FASDKYOPVNHBLU-UHFFFAOYSA-N | C10H17N3S | 211.327 | 4 / 2 | 1.9 | Yes |
| 76576 |  Zacopride | C15H20ClN3O2 | 309.794 | 4 / 2 | 1.7 | Yes |
| 472338 |  CHEMBL3609142 | C31H35NO4 | 485.624 | 5 / 0 | 7.0 | No |
| 76733 |  MLS000058692 | C13H7ClN6S2 | 346.811 | 7 / 0 | 4.2 | Yes |
| 559768 |  MLS000064957 | C17H16N2O3S | 328.386 | 5 / 2 | 2.9 | Yes |
| 80446 |  CHEMBL282829 | C20H24N4 | 320.44 | 3 / 1 | 3.5 | Yes |
| 81986 |  SMR000102200 | C21H28N2O3 | 356.466 | 5 / 1 | 3.7 | Yes |
| 83617 |  CHEMBL2205813 | C21H25NO3 | 339.435 | 4 / 1 | 2.8 | Yes |
| 83689 |  MLS000086722 | C17H25N3O2S | 335.466 | 4 / 1 | 2.9 | Yes |
| 83885 |  Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
| 538071 |  CHEMBL286739 | C13H16ClN5O3 | 325.753 | 7 / 4 | 0.2 | Yes |
| 84730 |  CHEMBL2024087 | C14H20N2O2 | 248.326 | 4 / 2 | 0.9 | Yes |
| 86480 |  4'-Aminopropiophenone | C9H11NO | 149.193 | 2 / 1 | 1.7 | Yes |
| 87217 |  SMR000102159 | C19H23FN2O2 | 330.403 | 5 / 0 | 3.4 | Yes |
| 87358 |  BDBM31035 | C23H25N3O6 | 439.468 | 6 / 2 | 2.3 | Yes |
| 88150 |  MLS000392370 | C22H17Cl2NO3 | 414.282 | 3 / 1 | 6.0 | No |
| 89676 |  CHEMBL17828 | C35H42N6O2 | 578.761 | 4 / 6 | 4.0 | No |
| 89742 |  Brolamfetamine | C11H16BrNO2 | 274.158 | 3 / 1 | 2.6 | Yes |
| 90159 |  SMR000019649 | C25H29N3O4S | 467.584 | 7 / 1 | 4.1 | Yes |
| 90933 |  CHEMBL1643900 | C19H22FN | 283.39 | 2 / 1 | 3.9 | Yes |
| 91162 |  CHEMBL1258722 | C23H30N4O2 | 394.519 | 4 / 0 | 3.8 | Yes |
| 91451 |  CHEMBL1643901 | C19H22FN | 283.39 | 2 / 0 | 3.9 | Yes |
| 474366 |  CHEMBL3609146 | C25H23NO4 | 401.462 | 5 / 1 | 4.4 | Yes |
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