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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000078951
Molecular formula	C21H22N2O3
IUPAC name	2-[3-(furan-2-carbonyl)indol-1-yl]-1-(2-methylpiperidin-1-yl)ethanone
Molecular weight	350.418
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.6
Synonyms	2-[3-(furan-2-carbonyl)indol-1-yl]-1-(2-methylpiperidin-1-yl)ethanone BAS 08196794 MCULE-8647374477 2-[3-[2-furanyl(oxo)methyl]-1-indolyl]-1-(2-methyl-1-piperidinyl)ethanone MolPort-002-012-404 2-[3-(2-furoyl)indol-1-yl]-1-(2-methylpiperidino)ethanone AKOS000465637 HMS2165J19 2-[3-(furan-2-ylcarbonyl)-1H-indol-1-yl]-1-(2-methylpiperidin-1-yl)ethanone BDBM31348 MLS000065297 CHEMBL1581164 2-[3-(Furan-2-carbonyl)-indol-1-yl]-1-(2-methyl-piperidin-1-yl)-ethanone AKOS022012129 HMS3309J04 2-[3-(furan-2-ylcarbonyl)indol-1-yl]-1-(2-methylpiperidin-1-yl)ethanone CCG-119605 MLS002547371 2-furyl{1-[2-(2-methyl-1-piperidinyl)-2-oxoethyl]-1H-indol-3-yl}methanone AC1MGP7Y cid_2964527 STL505484 [ Show all ]
Inchi Key	DDFKIBRAGFANTI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22N2O3/c1-15-7-4-5-11-23(15)20(24)14-22-13-17(16-8-2-3-9-18(16)22)21(25)19-10-6-12-26-19/h2-3,6,8-10,12-13,15H,4-5,7,11,14H2,1H3
PubChem CID	2964527
ChEMBL	CHEMBL1581164
IUPHAR	N/A
BindingDB	31348
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
57040	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
57039	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
57038	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
57037	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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