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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB-357134
Molecular formula	C17H18Br2FN3O3S
IUPAC name	N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
Molecular weight	523.215
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.4
Synonyms	N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-(piperazin-1-yl)benzenesulfonamide SCHEMBL678563 GTPL3235 PDSP2_001358 AC1OCFKU N-(2,5-dibromo-3-fluorophe-nyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide CHEMBL329383 N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide L020233 SB 357134 BDBM50130268 N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-(piperazin-1-yl)benzene-1-sulfonamide SB357134 D0H7PC PDSP1_001374 N-(2,5-Dibromo-3-fluoro-phenyl)-4-methoxy-3-piperazin-1-yl-benzenesulfonamide SB-357,134 [ Show all ]
Inchi Key	BLWHAZZXRHTFJE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18Br2FN3O3S/c1-26-16-3-2-12(10-15(16)23-6-4-21-5-7-23)27(24,25)22-14-9-11(18)8-13(20)17(14)19/h2-3,8-10,21-22H,4-7H2,1H3
PubChem CID	6918553
ChEMBL	CHEMBL329383
IUPHAR	3235
BindingDB	50130268
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
27049	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
27050	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
27048	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
27038	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
27047	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
27044	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
27041	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
27040	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
27053	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
27042	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
27043	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
27052	5-hydroxytryptamine receptor 6	Q9R1C8	Htr6	Mus musculus (Mouse)	440
27045	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
27039	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
27046	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
27051	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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