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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	naratriptan
Molecular formula	C17H25N3O2S
IUPAC name	N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide
Molecular weight	335.466
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.0
Synonyms	Amerge (TN) BCP9000978 CS-2131 GTPL45 N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide Naratriptan (INN) QX3KXL1ZA2 A25336 AMKVXSZCKVJAGH-UHFFFAOYSA-N C07792 L000432 N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide naratriptanum UNII-QX3KXL1ZA2 1H-Indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)- ABP000374 AJ-08192 AX8017803 CHEMBL1278 FC0032 N-methyl-2-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)ethane-1-sulfonamide Naramig (TN) NCGC00181786-04 Amerge, Naramig,Naratriptan BDBM50073682 D08255 HY-B0197 N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide Naratriptan [INN:BAN] SC-00604 AB01565792_02 AN-11431 CHEBI:7478 DB00952 LS-83062 N-Methyl-3-(1-methyl-4 -piperidinyl)-1H-indole-5-ethansulphonamide NCGC00181786-01 ZINC4076 2-[3-(1-Methyl-piperidin-4-yl)-1H-indol-5-yl]-ethanesulfonic acid methylamide AC-5013 AKOS015895854 BC201774 Colatan FT-0656760 N-Methyl-2-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)ethanesulfonamide PubChem2191 Amerge;Naramig BIDD:GT0312 D0T3KI InChI=1/C17H25N3O2S/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14/h3-4,11-12,14,18-19H,5-10H2,1-2H N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide naratriptan; SCHEMBL68753 121679-13-8 AB2000122 AC1L1I6A API0005359 DTXSID7023354 N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulphonamide NCGC00181786-03 2578AH [ Show all ]
Inchi Key	AMKVXSZCKVJAGH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H25N3O2S/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14/h3-4,11-12,14,18-19H,5-10H2,1-2H3
PubChem CID	4440
ChEMBL	CHEMBL1278
IUPHAR	45
BindingDB	50073682
DrugBank	DB00952
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9005	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
9004	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
9003	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
553291	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
9001	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366

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