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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000025686
Molecular formula	C23H24ClN3O3
IUPAC name	5-chloro-3-[2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-oxoethyl]-1H-indole-2-carboxylic acid
Molecular weight	425.913
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.3
Synonyms	5-chloro-3-[2-[4-(2,3-dimethylphenyl)piperazino]-2-keto-ethyl]-1H-indole-2-carboxylic acid HMS2306J21 AKOS001783894 REGID_for_CID_3237041 5-chloro-3-[2-[4-(2,3-dimethylphenyl)-1-piperazinyl]-2-oxoethyl]-1H-indole-2-carboxylic acid CHEMBL1373172 5-chloro-3-{2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-1H-indole-2-carboxylic acid MLS000091124 BDBM31020 5-chloro-3-[2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-oxoethyl]-1H-indole-2-carboxylic acid cid_3237041 AC1MMDHT MLS000876711 5-chloranyl-3-[2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-oxidanylidene-ethyl]-1H-indole-2-carboxylic acid [ Show all ]
Inchi Key	DKPWDKDIPZQOLB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H24ClN3O3/c1-14-4-3-5-20(15(14)2)26-8-10-27(11-9-26)21(28)13-18-17-12-16(24)6-7-19(17)25-22(18)23(29)30/h3-7,12,25H,8-11,13H2,1-2H3,(H,29,30)
PubChem CID	3237041
ChEMBL	CHEMBL1373172
IUPHAR	N/A
BindingDB	31020
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62521	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
62524	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
62523	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
62522	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378

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