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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3959210
Molecular formula	C14H18ClN5O3
IUPAC name	(1R,2R,3S,4R,5S)-4-[2-chloro-6-(dimethylamino)purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol
Molecular weight	339.78
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	0.3
Synonyms	BDBM50199474
Inchi Key	BSBLYPMZOLQTAO-RUVJYUCVSA-N
Inchi ID	InChI=1S/C14H18ClN5O3/c1-19(2)11-7-12(18-13(15)17-11)20(5-16-7)8-6-3-14(6,4-21)10(23)9(8)22/h5-6,8-10,21-23H,3-4H2,1-2H3/t6-,8-,9+,10+,14+/m1/s1
PubChem CID	134155462
ChEMBL	CHEMBL3959210
IUPHAR	N/A
BindingDB	50199474
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
548240	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
548236	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
548243	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
548237	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
548239	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
548235	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
548245	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
548238	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
548244	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
548242	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
548233	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
548241	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
548234	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412

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