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| Name | 5-hydroxytryptamine receptor 5A |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | HTR5A |
| Synonym | 5-HT5alpha 5-HT-5 MR22 Htr5 5-HT-5A [ Show all ] |
| Disease | N/A |
| Length | 357 |
| Amino acid sequence | MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH |
| UniProt | P47898 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P47898 |
| 3D structure model | This predicted structure model is from GPCR-EXP P47898. |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3426 |
| IUPHAR | 10 |
| DrugBank | BE0004688 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 1031 |  CHEMBL2205816 | C18H20N2O | 280.371 | 3 / 1 | 1.8 | Yes |
| 1473 |  4365 CT | C14H20N2O | 232.327 | 2 / 1 | 2.7 | Yes |
| 2275 |  1-(cyclohexylmethyl)pyrrolidine | C11H21N | 167.296 | 1 / 0 | 3.1 | Yes |
| 2916 |  CHEMBL446459 | C14H19F2N3O | 283.323 | 4 / 2 | 2.6 | Yes |
| 3142 |  AC1N0YGA | C3H7NO4S | 153.152 | 5 / 2 | -4.7 | Yes |
| 3679 |  MLS001172392 | C16H17Cl2N3O | 338.232 | 3 / 1 | 3.3 | Yes |
| 3715 |  AC1NW0NQ | C14H13NO4S | 291.321 | 5 / 0 | 2.5 | Yes |
| 5006 |  CHEMBL130585 | C21H23N3O3 | 365.433 | 4 / 0 | 3.8 | Yes |
| 5516 |  CHEMBL188440 | C36H40F3N3O4S | 667.788 | 10 / 2 | N/A | No |
| 6621 |  MLS000401592 | C26H21FN4O5S2 | 552.595 | 9 / 3 | 5.1 | No |
| 463736 |  CHEMBL3633757 | C26H24BrNO4 | 494.385 | 5 / 0 | 5.4 | No |
| 536140 |  CHEMBL3899832 | C22H19N5O4 | 417.425 | 8 / 2 | 3.6 | Yes |
| 8184 |  CHEMBL186450 | C34H34F3N3O4 | 605.658 | 9 / 2 | N/A | No |
| 521691 |  CHEMBL3754496 | C16H19FN2 | 258.34 | 2 / 1 | 2.9 | Yes |
| 10716 |  CHEMBL3287723 | C25H32O7 | 444.524 | 7 / 2 | 5.7 | No |
| 11605 |  MLS000735366 | C21H28N2O3S | 388.526 | 6 / 0 | 3.8 | Yes |
| 553308 |  Propranolol, L- | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 11968 |  Alfentanil hydrochloride | C21H33ClN6O3 | 452.984 | 6 / 1 | N/A | N/A |
| 12460 |  CHEMBL338696 | C22H25FN2O | 352.453 | 3 / 1 | 3.6 | Yes |
| 13654 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 15126 |  106674-03-7 | C27H20N2O8S | 532.523 | 8 / 1 | 3.9 | No |
| 15204 |  CHEMBL3654211 | C17H14F4N4O | 366.32 | 5 / 2 | 2.7 | Yes |
| 15474 |  CHEMBL2205829 | C19H19NO3 | 309.365 | 4 / 1 | 2.2 | Yes |
| 15561 |  MLS000731975 | C24H31N3O2 | 393.531 | 5 / 0 | 4.1 | Yes |
| 15738 |  MLS000731911 | C23H28FN3OS | 413.555 | 5 / 0 | 4.6 | Yes |
| 521954 |  AM-0902 | C17H15ClN6O2 | 370.797 | 6 / 0 | 2.3 | Yes |
| 16325 |  CHEMBL272752 | C8H8ClN3 | 181.623 | 1 / 2 | 0.8 | Yes |
| 17248 |  CHEMBL536561 | C9H12IN3O | 305.119 | 2 / 3 | N/A | N/A |
| 20402 |  CHEMBL338095 | C21H22ClFN2O | 372.868 | 3 / 0 | 4.7 | Yes |
| 20826 |  SMR000211820 | C23H21N5O2 | 399.454 | 6 / 0 | 4.4 | Yes |
| 21857 |  CHEMBL126737 | C21H22ClFN2O | 372.868 | 3 / 0 | 4.7 | Yes |
| 522111 |  CHEMBL3775436 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 522164 |  CHEMBL3775769 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 22552 |  CHEMBL283036 | C19H19F3N4 | 360.384 | 6 / 1 | 3.6 | Yes |
| 23172 |  1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | C11H16INO2 | 321.158 | 3 / 1 | 2.5 | Yes |
| 24292 |  CHEMBL2181168 | C21H24IN3O | 461.347 | 4 / 0 | 5.1 | No |
| 24617 |  SMR000160814 | C24H18BrN3O4 | 492.329 | 5 / 2 | 5.1 | No |
| 536618 |  2-Chloroadenosine | C10H12ClN5O4 | 301.687 | 8 / 4 | -0.1 | Yes |
| 24868 |  MLS000733666 | C25H29NO3 | 391.511 | 4 / 1 | 4.3 | Yes |
| 558067 |  MLS000587743 | C17H13BrF3N3O5 | 476.206 | 9 / 2 | 3.8 | Yes |
| 26308 |  CHEMBL600053 | C18H18FNO | 283.346 | 3 / 1 | 2.5 | Yes |
| 553397 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 27192 |  CHEMBL2203713 | C18H22N4S | 326.462 | 4 / 2 | 2.9 | Yes |
| 27494 |  CHEMBL2432063 | C19H29N | 271.448 | 1 / 0 | 4.7 | Yes |
| 28762 |  CHEMBL320412 | C17H26N4O2S | 350.481 | 5 / 2 | 1.6 | Yes |
| 29351 |  SMR000005041 | C23H33ClN6OS | 477.068 | 7 / 1 | N/A | N/A |
| 29496 |  MLS001239230 | C25H31ClF2N4O3S2 | 573.115 | 9 / 1 | N/A | No |
| 30513 |  MLS000948488 | C22H18Cl3N3S | 462.817 | 4 / 1 | N/A | N/A |
| 548244 |  CHEMBL3959210 | C14H18ClN5O3 | 339.78 | 7 / 3 | 0.3 | Yes |
| 32133 |  aspirin | C9H8O4 | 180.159 | 4 / 1 | 1.2 | Yes |
| 32510 |  UNII-QQYOR9S587 | C18H29NO | 275.436 | 2 / 0 | 4.8 | Yes |
| 32852 |  Phencyclidine hydrochloride | C17H26ClN | 279.852 | 1 / 1 | N/A | N/A |
| 33475 |  UNII-7W7511NPF8 | C20H20N2O3S | 368.451 | 6 / 1 | 1.8 | Yes |
| 35246 |  HARMINE | C13H12N2O | 212.252 | 2 / 1 | 3.6 | Yes |
| 37190 |  CHEMBL187621 | C34H38N4O | 518.705 | 4 / 1 | 5.3 | No |
| 37625 |  CHEMBL103371 | C17H26N4O2S | 350.481 | 5 / 1 | 1.6 | Yes |
| 38755 |  MLS001197120 | C24H20N2O4 | 400.434 | 4 / 2 | 4.7 | Yes |
| 39055 |  CHEMBL126823 | C21H24N2O | 320.436 | 2 / 0 | 3.9 | Yes |
| 39074 |  CHEMBL186849 | C35H45F3N4O3 | 626.765 | 9 / 2 | N/A | No |
| 39625 |  SMR000176430 | C25H27Cl2N3O | 456.411 | 2 / 2 | N/A | N/A |
| 39852 |  MLS002701634 | C20H12O3 | 300.313 | 3 / 1 | 3.6 | Yes |
| 39920 |  SCHEMBL9104672 | C18H15FN4O | 322.343 | 3 / 2 | 3.1 | Yes |
| 40298 |  Aripiprazole | C23H27Cl2N3O2 | 448.388 | 4 / 1 | 4.6 | Yes |
| 40969 |  16502-01-5 | C11H12N2 | 172.231 | 1 / 2 | 1.5 | Yes |
| 41077 |  CHEMBL476838 | C23H29FN2O5 | 432.492 | 7 / 1 | 3.9 | Yes |
| 41558 |  MLS000720325 | C17H22N4S | 314.451 | 3 / 2 | 2.4 | Yes |
| 42467 |  CHEMBL2432039 | C20H23N | 277.411 | 1 / 1 | 2.7 | Yes |
| 42819 |  CHEMBL539103 | C8H9FIN3 | 293.084 | 2 / 3 | N/A | N/A |
| 43327 |  CHEMBL481153 | C19H20N2O2S | 340.441 | 4 / 0 | 3.9 | Yes |
| 43590 |  CHEMBL403103 | C16H22N4O | 286.379 | 2 / 2 | 1.6 | Yes |
| 44026 |  CHEMBL2432060 | C21H26FN | 311.444 | 2 / 0 | 4.8 | Yes |
| 44986 |  CHEMBL3654203 | C17H17F2N5O | 345.354 | 4 / 2 | 1.9 | Yes |
| 45049 |  MLS000552833 | C34H38N4O5 | 582.701 | 5 / 3 | 5.0 | No |
| 45416 |  CHEMBL1275709 | C16H19N3 | 253.349 | 2 / 1 | 2.8 | Yes |
| 45427 |  CHEMBL3654206 | C19H17F3N4O | 374.367 | 4 / 2 | 2.9 | Yes |
| 45776 |  23981-80-8 | C14H14O3 | 230.263 | 3 / 1 | 3.3 | Yes |
| 47474 |  CHEMBL2432051 | C21H27NO3 | 341.451 | 4 / 1 | 3.3 | Yes |
| 48444 |  CHEMBL1210154 | C19H16N2O2S | 336.409 | 4 / 1 | 4.7 | Yes |
| 459654 |  SCHEMBL4318956 | C19H16N2O2S | 336.409 | 4 / 1 | 4.7 | Yes |
| 49040 |  SCHEMBL9106401 | C17H11ClF2N4O | 360.749 | 4 / 2 | 3.5 | Yes |
| 51035 |  SCHEMBL9105330 | C17H12ClFN4O | 342.758 | 3 / 2 | 3.4 | Yes |
| 558895 |  Harmalan | C12H12N2 | 184.242 | 1 / 1 | 2.1 | Yes |
| 52465 |  CHEMBL258075 | C12H17N3O | 219.288 | 2 / 2 | 1.3 | Yes |
| 52572 |  CHEMBL590615 | C19H20FNO | 297.373 | 3 / 1 | 3.0 | Yes |
| 52909 |  CHEMBL1829958 | C12H9BrN4O | 305.135 | 4 / 3 | 2.3 | Yes |
| 469513 |  CHEMBL3609143 | C29H29NO4 | 455.554 | 5 / 0 | 5.4 | No |
| 53791 |  {4-[(3-fluorophenyl)methoxy]phenyl}methanamine hydrochloride | C14H15ClFNO | 267.728 | 3 / 2 | N/A | N/A |
| 54075 |  ST-1535 | C12H16N8 | 272.316 | 6 / 1 | 1.8 | Yes |
| 469620 |  CHEMBL3608451 | C27H27NO4 | 429.516 | 5 / 0 | 5.1 | No |
| 54539 |  MLS000733242 | C23H21FN4O | 388.446 | 5 / 1 | 3.4 | Yes |
| 54689 |  MLS002320705 | C35H49NO10 | 643.774 | 11 / 5 | 1.1 | No |
| 55625 |  fenfluramine | C12H16F3N | 231.262 | 4 / 1 | 3.4 | Yes |
| 56332 |  CHEMBL2205833 | C17H18N2O | 266.344 | 3 / 1 | 1.3 | Yes |
| 56946 |  CHEMBL421283 | C22H26N2O | 334.463 | 2 / 1 | 4.6 | Yes |
| 523216 |  CHEMBL3770342 | C14H18BrN5 | 336.237 | 2 / 3 | 2.3 | Yes |
| 57991 |  CHEMBL2432053 | C19H22N2O | 294.398 | 3 / 0 | 2.0 | Yes |
| 59237 |  MLS000547944 | C19H21ClN4 | 340.855 | 3 / 0 | 3.5 | Yes |
| 60516 |  CHEMBL253597 | C21H20N2O3 | 347.402 | 4 / 0 | 3.2 | Yes |
| 61026 |  6,8,9-trimethyl-11H-indolo[3,2-c]quinoline | C18H16N2 | 260.34 | 1 / 1 | 4.8 | Yes |
| 61270 |  CHEMBL3262407 | C20H27N3O | 325.456 | 4 / 1 | 3.7 | Yes |
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