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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Propranolol, L-
Molecular formula	C16H21NO2
IUPAC name	(2S)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol
Molecular weight	259.349
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.0
Synonyms	AB00514695-07 Bio2_000840 BSPBio_001122 HMS1792D21 KBio3_000740 NCGC00024813-03 Prestwick0_001081 SCHEMBL3956 1-propranolol AJ-09309 BRD-K13994703-001-02-0 CHEMBL452861 IDI1_002115 Levopropranolol NCGC00024813-06 Prestwick3_001075 UNII-74MLR03FLC (2S)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol 4199-09-1 74MLR03FLC BDBM50246936 BSPBio_001040 GTPL63 KBio2_005516 NCGC00024813-01 PDSP1_000768 S-(-)-propanolol [2-Hydroxy-3-(naphthalen-1-yloxy)-propyl]-isopropyl-ammonium((-)-propranolol) 1-((1-methylethyl)amino) 3-(1-naphthalenyloxy) 2-propanol AB00514695_08 BPBio1_001200 CCG-205103 HMS1990D21 KBioGR_000380 NCGC00024813-04 Prestwick1_001081 SPBio_003021 (-)-(S)-Propranolol 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, (S)- AQHHHDLHHXJYJD-AWEZNQCLSA-N BRD-K13994703-003-04-2 CTK4I5506 KBio2_000380 Lopac0_001023 NCGC00024813-07 Prestwick3_001081 UNII-9Y8NXQ24VQ component AQHHHDLHHXJYJD-AWEZNQCLSA-N (S)-1-(Isopropylamino)-3-(naphthyloxy)propan-2-ol AB00514695 Bio2_000360 BSPBio_001090 HMS1362D21 KBio3_000739 NCGC00024813-02 PDSP2_000756 SBI-0050996.P003 1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol AC1L3M9V BPBio1_001236 HMS2089B07 KBioSS_000380 NCGC00024813-05 Prestwick2_001081 Tocris-0834 (-)-propranolol 2-Propanol,1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, (2S)- BCBcMAP01_000208 BRD-K13994703-003-10-9 EINECS 224-095-5 KBio2_002948 LS-122524 NCGC00024813-08 ZINC56556 (S)-propranolol [ Show all ]
Inchi Key	AQHHHDLHHXJYJD-AWEZNQCLSA-N
Inchi ID	InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3/t14-/m0/s1
PubChem CID	91536
ChEMBL	CHEMBL452861
IUPHAR	63
BindingDB	50246936
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11695	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
553307	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
11699	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
11703	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
11691	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
11700	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
11693	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
11692	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
553308	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
11701	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
11694	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
11697	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
11698	Beta-2 adrenergic receptor	Q28044	ADRB2	Bos taurus (Bovine)	418
11696	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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