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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000733242
Molecular formula	C23H21FN4O
IUPAC name	N-[[3-(3-fluorophenyl)-1-(4-methoxyphenyl)pyrazol-4-yl]methyl]-1-pyridin-3-ylmethanamine
Molecular weight	388.446
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.4
Synonyms	MCULE-4430161814 BDBM72389 N-[[3-(3-fluorophenyl)-1-(4-methoxyphenyl)pyrazol-4-yl]methyl]-1-pyridin-3-yl-methanamine cid_16187264 SMR000315894 1-[3-(3-fluorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-4-yl]-N-(pyridin-3-ylmethyl)methanamine N-[[3-(3-fluorophenyl)-1-(4-methoxyphenyl)pyrazol-4-yl]methyl]-1-pyridin-3-ylmethanamine HMS2706B20 [3-(3-fluorophenyl)-1-(4-methoxyphenyl)pyrazol-4-yl]methyl-(3-pyridylmethyl)amine N-[[3-(3-fluorophenyl)-1-(4-methoxyphenyl)-4-pyrazolyl]methyl]-1-(3-pyridinyl)methanamine CHEMBL1403842 Opera_ID_676 [ Show all ]
Inchi Key	CZPUVLUVRJNPPC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H21FN4O/c1-29-22-9-7-21(8-10-22)28-16-19(15-26-14-17-4-3-11-25-13-17)23(27-28)18-5-2-6-20(24)12-18/h2-13,16,26H,14-15H2,1H3
PubChem CID	16187264
ChEMBL	CHEMBL1403842
IUPHAR	N/A
BindingDB	72389
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
54539	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
54537	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
54538	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
54540	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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