You can:
| Name | Delta-type opioid receptor |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | OPRD1 |
| Synonym | D-OR-1 DOR opioid receptor OP1 DOP [ Show all ] |
| Disease | Cough Overactive bladder disorder Bladder disease Moderate-to-severe pain Diarrhea-predominant IBS [ Show all ] |
| Length | 372 |
| Amino acid sequence | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA |
| UniProt | P41143 |
| Protein Data Bank | 4rwd, 4rwa, 4n6h |
| GPCR-HGmod model | P41143 |
| 3D structure model | This structure is from PDB ID 4rwd. |
| BioLiP | BL0303696,BL0303697, BL0265712, BL0265705,BL0265706,BL0265707,, BL0303699,BL0303701, BL0303698,BL0303700 |
| Therapeutic Target Database | T58992 |
| ChEMBL | CHEMBL236 |
| IUPHAR | 317 |
| DrugBank | BE0000420 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 169 |  CHEMBL2381177 | C30H37N3O4 | 503.643 | 6 / 3 | 5.8 | No |
| 441673 |  CHEMBL3409110 | C29H32FNO2 | 445.578 | 4 / 1 | 7.1 | No |
| 207 |  MLS002473569 | C22H18N2O3S2 | 422.517 | 5 / 0 | 4.0 | Yes |
| 322 |  CHEMBL412600 | C61H96N20O13 | 1317.57 | 17 / 18 | -3.5 | No |
| 325 |  CHEMBL387083 | C61H96N20O13 | 1317.57 | 17 / 18 | -3.5 | No |
| 435 |  CHEMBL2311023 | C63H106N22O11 | 1347.68 | 17 / 19 | -2.5 | No |
| 470 |  CHEMBL1642761 | C24H30N2 | 346.518 | 2 / 1 | 5.4 | No |
| 521450 |  CHEMBL3759541 | C35H36N4O4 | 576.697 | 5 / 3 | 4.7 | No |
| 567 |  CHEMBL438965 | C25H25ClN2 | 388.939 | 1 / 1 | 6.4 | No |
| 692 |  CHEMBL76086 | C31H41N5O7S2 | 659.817 | 10 / 7 | -0.3 | No |
| 698 |  CHEMBL310681 | C31H41N5O7S2 | 659.817 | 10 / 7 | -0.3 | No |
| 702 |  CHEMBL80626 | C31H41N5O7S2 | 659.817 | 10 / 7 | -0.3 | No |
| 707 |  CHEMBL307614 | C31H41N5O7S2 | 659.817 | 10 / 7 | -0.3 | No |
| 725 |  CHEMBL307327 | C27H34N2O2 | 418.581 | 3 / 0 | 5.2 | No |
| 861 |  CHEMBL125742 | C23H31N3O2 | 381.52 | 4 / 1 | 3.0 | Yes |
| 948 |  CHEMBL2397017 | C30H29N3O4 | 495.579 | 6 / 2 | 4.2 | Yes |
| 1006 |  CHEMBL2205816 | C18H20N2O | 280.371 | 3 / 1 | 1.8 | Yes |
| 557338 |  SCHEMBL16034373 | C29H39N3O6 | 525.646 | 7 / 4 | 1.7 | No |
| 547914 |  CHEMBL3899312 | C29H39N3O6 | 525.646 | 7 / 4 | 1.7 | No |
| 1378 |  CHEMBL235154 | C22H21N3O2 | 359.429 | 4 / 1 | 3.0 | Yes |
| 1436 |  CHEMBL1929362 | C27H30N2O | 398.55 | 3 / 1 | 5.8 | No |
| 1514 |  CHEMBL556537 | C70H89F6N11O15 | 1438.53 | 22 / 14 | 5.8 | No |
| 1531 |  SB-0304 | C25H29N5O5 | 479.537 | 6 / 4 | -0.2 | Yes |
| 521477 |  CHEMBL3814950 | C26H36N4O2 | 436.6 | 5 / 3 | 3.5 | Yes |
| 1567 |  CHEMBL2158955 | C47H61N9O8S | 912.12 | 10 / 9 | 3.2 | No |
| 1650 |  CHEMBL25493 | C18H24Cl2N2O | 355.303 | 2 / 1 | 4.1 | Yes |
| 2150 |  CHEMBL188841 | C14H21NO | 219.328 | 2 / 1 | 3.2 | Yes |
| 2175 |  CHEMBL493781 | C19H23N5O | 337.427 | 5 / 1 | 2.0 | Yes |
| 2276 |  1-(cyclohexylmethyl)pyrrolidine | C11H21N | 167.296 | 1 / 0 | 3.1 | Yes |
| 547925 |  CHEMBL3977305 | C27H31NO4 | 433.548 | 5 / 2 | 3.8 | Yes |
| 557371 |  SCHEMBL878409 | C27H31NO4 | 433.548 | 5 / 2 | 3.8 | Yes |
| 547926 |  CHEMBL3945795 | C15H25NO | 235.371 | 2 / 0 | 2.6 | Yes |
| 463226 |  CHEMBL3609619 | C32H30F6N4O5 | 664.605 | 12 / 5 | 4.5 | No |
| 2966 |  CHEMBL415223 | C37H44N2O2 | 548.771 | 3 / 2 | 8.1 | No |
| 3002 |  CHEMBL294134 | C31H42N6O8 | 626.711 | 9 / 8 | -2.2 | No |
| 3174 |  CHEMBL557188 | C60H72F6N10O9 | 1191.29 | 16 / 10 | 7.4 | No |
| 441840 |  CHEMBL3361419 | C24H34N6O3 | 454.575 | 6 / 4 | 1.7 | Yes |
| 3182 |  CHEMBL377340 | C18H19N3O | 293.37 | 3 / 1 | 4.1 | Yes |
| 535993 |  SCHEMBL1532866 | C18H23N3O2 | 313.401 | 4 / 2 | 2.6 | Yes |
| 3238 |  CHEMBL124642 | C23H31N3O | 365.521 | 3 / 0 | 3.5 | Yes |
| 3354 |  CHEMBL317269 | C23H31NO4 | 385.504 | 5 / 1 | 2.5 | Yes |
| 3486 |  CHEMBL66387 | C33H36N2O2 | 492.663 | 3 / 0 | 6.6 | No |
| 3526 |  CHEMBL38576 | C21H24Cl2N2O | 391.336 | 2 / 0 | 4.6 | Yes |
| 3532 |  CHEMBL320882 | C21H24Cl2N2O | 391.336 | 2 / 0 | 4.6 | Yes |
| 463318 |  MLS004801940 | C17H24BrN3O3 | 398.301 | 6 / 1 | 2.4 | Yes |
| 3568 |  CHEMBL231049 | C24H31N3O2 | 393.531 | 3 / 1 | 2.7 | Yes |
| 3678 |  MLS001172392 | C16H17Cl2N3O | 338.232 | 3 / 1 | 3.3 | Yes |
| 3710 |  AC1NW0NQ | C14H13NO4S | 291.321 | 5 / 0 | 2.5 | Yes |
| 3799 |  CHEMBL127463 | C25H24FN3O | 401.485 | 4 / 1 | 4.7 | Yes |
| 3865 |  CHEMBL228740 | C22H23NOS | 349.492 | 3 / 1 | 4.3 | Yes |
| 3900 |  CHEMBL2371018 | C38H40N4O6 | 648.76 | 7 / 5 | 2.3 | No |
| 3903 |  CHEMBL2371027 | C38H40N4O6 | 648.76 | 7 / 5 | 2.3 | No |
| 3937 |  CHEMBL364398 | C23H37N3O3S | 435.627 | 6 / 1 | 3.3 | Yes |
| 521556 |  CHEMBL3809808 | C26H29NO2 | 387.523 | 3 / 1 | 4.8 | Yes |
| 521564 |  CHEMBL3815013 | C25H34N4O2 | 422.573 | 5 / 3 | 3.0 | Yes |
| 4451 |  CHEMBL230943 | C27H31N3O2 | 429.564 | 3 / 1 | 4.1 | Yes |
| 4461 |  CHEMBL60270 | C17H24N2O | 272.392 | 3 / 2 | 2.7 | Yes |
| 4469 |  CHEMBL24293 | C25H27N3 | 369.512 | 3 / 0 | 4.5 | Yes |
| 4643 |  CHEMBL593613 | C21H26N4O | 350.466 | 4 / 1 | 4.5 | Yes |
| 4699 |  CHEMBL2334770 | C35H38N6O5 | 622.726 | 6 / 6 | 2.3 | No |
| 4706 |  CHEMBL2334768 | C35H38N6O5 | 622.726 | 6 / 6 | 2.3 | No |
| 4921 |  CHEMBL332697 | C23H24N4O6 | 452.467 | 6 / 1 | 2.7 | Yes |
| 4938 |  CHEMBL319589 | C28H29NO4 | 443.543 | 5 / 1 | 5.1 | No |
| 5002 |  CHEMBL296304 | C18H22N2 | 266.388 | 2 / 0 | 3.2 | Yes |
| 5175 |  MLS000714572 | C22H30N2O6 | 418.49 | 6 / 2 | 2.5 | Yes |
| 5204 |  Dynorphin B | C74H115N21O17 | 1570.86 | 21 / 22 | -3.6 | No |
| 5287 |  MLS000528029 | C20H20N2O5S | 400.449 | 6 / 2 | 3.7 | Yes |
| 463527 |  CHEMBL3597077 | C84H139N21O24 | 1827.16 | 28 / 25 | -4.1 | No |
| 5581 |  CHEMBL365483 | C22H27NO | 321.464 | 2 / 1 | 5.3 | No |
| 459270 |  CID 44364817 | C42H46N6O8 | 762.864 | 9 / 7 | 0.6 | No |
| 5588 |  CHEMBL2370988 | C42H46N6O8 | 762.864 | 9 / 7 | 0.6 | No |
| 5591 |  CHEMBL2370989 | C42H46N6O8 | 762.864 | 9 / 7 | 0.6 | No |
| 5688 |  AC1L1HUK | C29H28ClN3O4 | 518.01 | 4 / 2 | 5.2 | No |
| 463566 |  CHEMBL3613884 | C27H34F3N3O3 | 505.582 | 8 / 2 | N/A | No |
| 5821 |  H-Aba-Gly-Gly-Phe-Leu-OH | C29H37N7O6S | 611.718 | 10 / 7 | -0.2 | No |
| 5838 |  BDBM50321606 | C80H98N18O14 | 1535.78 | 17 / 18 | 2.2 | No |
| 5870 |  CHEMBL347750 | C21H28N2O2 | 340.467 | 3 / 3 | 3.5 | Yes |
| 557446 |  SCHEMBL14466685 | C27H30N4O4 | 474.561 | 6 / 4 | 2.3 | Yes |
| 6020 |  CHEMBL230253 | C23H31NO | 337.507 | 2 / 1 | 5.3 | No |
| 6054 |  CHEMBL195285 | C22H28N2O4 | 384.476 | 5 / 2 | 0.9 | Yes |
| 6182 |  CHEMBL61426 | C24H23F3N2O2 | 428.455 | 6 / 0 | 5.3 | No |
| 6200 |  CHEMBL307235 | C23H28Cl2N2O3 | 451.388 | 4 / 0 | 4.5 | Yes |
| 6203 |  CHEMBL70311 | C23H28Cl2N2O3 | 451.388 | 4 / 0 | 4.5 | Yes |
| 6350 |  CHEMBL2163917 | C33H36N6O6 | 612.687 | 7 / 6 | 1.5 | No |
| 6403 |  hesperetin | C16H14O6 | 302.282 | 6 / 3 | 2.4 | Yes |
| 441937 |  CHEMBL3394008 | C18H22N6O3S | 402.473 | 6 / 2 | 0.7 | Yes |
| 6490 |  3-(4-methylpiperazin-1-yl)phenol | C11H16N2O | 192.262 | 3 / 1 | 1.5 | Yes |
| 6622 |  MLS000401592 | C26H21FN4O5S2 | 552.595 | 9 / 3 | 5.1 | No |
| 6666 |  CHEMBL265195 | C28H29NO10 | 539.537 | 10 / 0 | 4.0 | No |
| 6783 |  spiropiperidine analogue, 11 | C28H31N3O | 425.576 | 3 / 0 | 5.4 | No |
| 463684 |  CHEMBL3597076 | C83H134N20O26 | 1828.1 | 29 / 25 | -6.6 | No |
| 6814 |  CHEMBL41098 | C38H42N4O8S2 | 746.894 | 12 / 4 | 2.1 | No |
| 6818 |  KUC104543N | C26H30N6O2 | 458.566 | 5 / 1 | 2.7 | Yes |
| 6921 |  CHEMBL382597 | C36H45N3O3 | 567.774 | 5 / 3 | 6.0 | No |
| 6935 |  MCL-145 | C46H58N2O4 | 702.98 | 6 / 0 | 10.6 | No |
| 6939 |  CHEMBL146756 | C46H58N2O4 | 702.98 | 6 / 0 | 10.6 | No |
| 463716 |  CHEMBL3633757 | C26H24BrNO4 | 494.385 | 5 / 0 | 5.4 | No |
| 7012 |  CHEMBL2322511 | C34H40N4O3 | 552.719 | 5 / 2 | 5.9 | No |
| 521653 |  CHEMBL3808879 | C27H31NO3 | 417.549 | 4 / 1 | 4.8 | Yes |
| 557487 |  SCHEMBL15486274 | C32H47NO7 | 557.728 | 8 / 0 | 3.4 | No |
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