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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000528029
Molecular formula	C20H20N2O5S
IUPAC name	N-[2,5-diethoxy-4-(thiophene-2-carbonylamino)phenyl]furan-2-carboxamide
Molecular weight	400.449
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.7
Synonyms	CHEMBL1404955 N-[2,5-diethoxy-4-(thiophene-2-carbonylamino)phenyl]furan-2-carboxamide AC1LRNFG HMS2162E17 SMR000120603 BDBM48458 N-[2,5-diethoxy-4-(2-thenoylamino)phenyl]-2-furamide cid_1374340 N-[2,5-diethoxy-4-[[oxo(thiophen-2-yl)methyl]amino]phenyl]-2-furancarboxamide AKOS000718859 HMS3325E06 ZINC1223642 N-[2,5-diethoxy-4-(thiophen-2-ylcarbonylamino)phenyl]furan-2-carboxamide Furan-2-carboxylic acid {2,5-diethoxy-4-[(thiophene-2-carbonyl)-amino]-phenyl}-amide Oprea1_698683 ASN 03019219 [ Show all ]
Inchi Key	AGWFGPCZMMBBOZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20N2O5S/c1-3-25-16-12-14(22-20(24)18-8-6-10-28-18)17(26-4-2)11-13(16)21-19(23)15-7-5-9-27-15/h5-12H,3-4H2,1-2H3,(H,21,23)(H,22,24)
PubChem CID	1374340
ChEMBL	CHEMBL1404955
IUPHAR	N/A
BindingDB	48458
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5287	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
5288	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332

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