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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL61426
Molecular formula	C24H23F3N2O2
IUPAC name	1-(1-phenyl-2-pyrrolidin-1-ylethyl)-3-[4-(trifluoromethoxy)phenyl]pyridin-2-one
Molecular weight	428.455
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.3
Synonyms	1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-(4-trifluoromethoxy-phenyl)-1H-pyridin-2-one BDBM50108444 1-(1-Phenyl-2-pyrrolizinoethyl)-3-[4-(trifluoromethoxy)phenyl]-1,2-dihydropyridine-2-one
Inchi Key	AIGBFJAZWRJQLT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H23F3N2O2/c25-24(26,27)31-20-12-10-18(11-13-20)21-9-6-16-29(23(21)30)22(17-28-14-4-5-15-28)19-7-2-1-3-8-19/h1-3,6-13,16,22H,4-5,14-15,17H2
PubChem CID	44302993
ChEMBL	CHEMBL61426
IUPHAR	N/A
BindingDB	50108444
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6182	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
6181	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
6180	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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