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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2381177
Molecular formula	C30H37N3O4
IUPAC name	3-hydroxy-N-[(2S)-1-[(3S)-4-(3-hydroxyphenyl)-3-methylpiperazin-1-yl]-3-methylbutan-2-yl]-4-(3-methylphenoxy)benzamide
Molecular weight	503.643
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	5.8
Synonyms	N/A
Inchi Key	AAFKOXZJMUODRO-WXVAWEFUSA-N
Inchi ID	InChI=1S/C30H37N3O4/c1-20(2)27(19-32-13-14-33(22(4)18-32)24-8-6-9-25(34)17-24)31-30(36)23-11-12-29(28(35)16-23)37-26-10-5-7-21(3)15-26/h5-12,15-17,20,22,27,34-35H,13-14,18-19H2,1-4H3,(H,31,36)/t22-,27+/m0/s1
PubChem CID	71681353
ChEMBL	CHEMBL2381177
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
169	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
168	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
167	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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