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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL317269
Molecular formula	C23H31NO4
IUPAC name	(10S)-17-(cyclopropylmethyl)-10-ethoxy-4-hydroxy-3-methoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one
Molecular weight	385.504
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.5
Synonyms	BDBM50032527 17-cyclopropylmethyl-10-ethoxy-4-hydroxy-3-methoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one
Inchi Key	AEDDGWOMKKVLRS-ZUEZHPSSSA-N
Inchi ID	InChI=1S/C23H31NO4/c1-3-28-23-9-8-17(25)13-22(23)10-11-24(14-15-4-5-15)19(23)12-16-6-7-18(26)21(27-2)20(16)22/h6-7,15,19,26H,3-5,8-14H2,1-2H3/t19?,22?,23-/m1/s1
PubChem CID	44334636
ChEMBL	CHEMBL317269
IUPHAR	N/A
BindingDB	50032527
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3354	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
3357	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
3355	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
3358	Kappa-type opioid receptor	P33534	Oprk1	Mus musculus (Mouse)	380
3353	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
3356	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398

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