You can:
| Name | Kappa-type opioid receptor |
|---|---|
| Species | Cavia porcellus (Guinea pig) |
| Gene | OPRK1 |
| Synonym | K-OR-1 KOR-1 |
| Disease | N/A for non-human GPCRs |
| Length | 380 |
| Amino acid sequence | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV |
| UniProt | P41144 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3952 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 320 |  CHEMBL412600 | C61H96N20O13 | 1317.57 | 17 / 18 | -3.5 | No |
| 327 |  CHEMBL387083 | C61H96N20O13 | 1317.57 | 17 / 18 | -3.5 | No |
| 433 |  CHEMBL2311023 | C63H106N22O11 | 1347.68 | 17 / 19 | -2.5 | No |
| 1087 |  CHEMBL1162502 | C24H39N3 | 369.597 | 1 / 0 | 5.9 | No |
| 1088 |  BDBM50271454 | C24H40N3+ | 370.605 | 0 / 1 | 5.5 | No |
| 1231 |  CHEMBL143800 | C23H25NO3 | 363.457 | 4 / 1 | 3.6 | Yes |
| 1437 |  CHEMBL1929362 | C27H30N2O | 398.55 | 3 / 1 | 5.8 | No |
| 1648 |  CHEMBL25493 | C18H24Cl2N2O | 355.303 | 2 / 1 | 4.1 | Yes |
| 1843 |  CHEMBL2310837 | C20H25ClN2O | 344.883 | 2 / 0 | 4.0 | Yes |
| 441749 |  CHEMBL3326662 | C33H50N6OS2 | 610.924 | 5 / 2 | 5.3 | No |
| 521512 |  CHEMBL3759981 | C43H51N7O7 | 777.923 | 8 / 8 | 3.4 | No |
| 3129 |  AC1N0YGA | C3H7NO4S | 153.152 | 5 / 2 | -4.7 | Yes |
| 557376 |  CHEMBL124642 | C23H31N3O | 365.521 | 3 / 0 | 3.5 | Yes |
| 3355 |  CHEMBL317269 | C23H31NO4 | 385.504 | 5 / 1 | 2.5 | Yes |
| 3465 |  CHEMBL434658 | C24H32N2O3 | 396.531 | 4 / 3 | 4.0 | Yes |
| 3520 |  CHEMBL106345 | C21H24Cl2N2O | 391.336 | 2 / 0 | 4.6 | Yes |
| 3523 |  CHEMBL38576 | C21H24Cl2N2O | 391.336 | 2 / 0 | 4.6 | Yes |
| 3531 |  CHEMBL320882 | C21H24Cl2N2O | 391.336 | 2 / 0 | 4.6 | Yes |
| 3802 |  CHEMBL127463 | C25H24FN3O | 401.485 | 4 / 1 | 4.7 | Yes |
| 3902 |  CHEMBL2371018 | C38H40N4O6 | 648.76 | 7 / 5 | 2.3 | No |
| 3905 |  CHEMBL2371027 | C38H40N4O6 | 648.76 | 7 / 5 | 2.3 | No |
| 4393 |  CHEMBL604522 | C21H25NO4 | 355.434 | 5 / 1 | 2.1 | Yes |
| 4427 |  CHEMBL2147922 | C25H24ClF3N2O2 | 476.924 | 7 / 3 | N/A | N/A |
| 4460 |  CHEMBL60270 | C17H24N2O | 272.392 | 3 / 2 | 2.7 | Yes |
| 4565 |  CHEMBL599323 | C21H27NO4 | 357.45 | 5 / 2 | 2.3 | Yes |
| 5001 |  CHEMBL296304 | C18H22N2 | 266.388 | 2 / 0 | 3.2 | Yes |
| 5205 |  Dynorphin B | C74H115N21O17 | 1570.86 | 21 / 22 | -3.6 | No |
| 5613 |  CHEMBL108344 | C21H22Cl2N2O | 389.32 | 2 / 0 | 4.4 | Yes |
| 6006 |  CHEMBL1834895 | C44H51N3O9 | 765.904 | 12 / 4 | 3.2 | No |
| 6008 |  CHEMBL1834901 | C44H51N3O9 | 765.904 | 12 / 4 | 3.2 | No |
| 6027 |  CHEMBL101072 | C37H54N4O3 | 602.864 | 5 / 4 | 5.9 | No |
| 6199 |  CHEMBL307235 | C23H28Cl2N2O3 | 451.388 | 4 / 0 | 4.5 | Yes |
| 6202 |  CHEMBL70311 | C23H28Cl2N2O3 | 451.388 | 4 / 0 | 4.5 | Yes |
| 441925 |  CHEMBL538308 | C22H31ClN2OS | 407.013 | 3 / 1 | N/A | N/A |
| 6359 |  CHEMBL300832 | C33H41BrN2O5S2 | 689.724 | 7 / 1 | N/A | No |
| 6766 |  CHEMBL1270475 | C27H28N2O2 | 412.533 | 4 / 2 | 4.1 | Yes |
| 6949 |  CHEMBL102013 | C42H63N5O3 | 685.998 | 5 / 4 | 7.3 | No |
| 7383 |  CHEMBL3215911 | C35H39Cl2N3O4 | 636.614 | 6 / 5 | N/A | No |
| 7758 |  CHEMBL610002 | C47H48N2O7 | 752.908 | 9 / 4 | 4.2 | No |
| 7764 |  BDBM50009130 | C47H48N2O7 | 752.908 | 9 / 4 | 4.2 | No |
| 7846 |  CHEMBL1797518 | C63H72N4O9 | 1029.29 | 13 / 3 | 8.2 | No |
| 7983 |  CHEMBL378753 | C26H27N3O4 | 445.519 | 6 / 3 | 3.5 | Yes |
| 7990 |  AC1L1I54 | C26H27N3O4 | 445.519 | 6 / 3 | 3.5 | Yes |
| 8016 |  CHEMBL2372400 | C27H36N4O7S | 560.666 | 9 / 4 | 0.5 | No |
| 8032 |  CHEMBL90463 | C20H29NO2 | 315.457 | 3 / 1 | 3.3 | Yes |
| 8096 |  CHEMBL2372387 | C26H34N4O7S | 546.639 | 9 / 5 | -0.4 | No |
| 9080 |  CHEMBL3298899 | C24H29N3O4 | 423.513 | 5 / 2 | 2.8 | Yes |
| 9367 |  CHEMBL60714 | C29H30N2O3 | 454.57 | 4 / 3 | 4.0 | Yes |
| 9426 |  CHEMBL553991 | C19H26ClF3N2O | 390.875 | 5 / 1 | N/A | N/A |
| 9626 |  CHEMBL2370497 | C63H107N23O11 | 1362.7 | 18 / 20 | -4.1 | No |
| 9657 |  CHEMBL543948 | C27H31ClN2O3 | 467.006 | 4 / 3 | N/A | N/A |
| 9757 |  CHEMBL92774 | C24H29NO2 | 363.501 | 3 / 1 | 4.8 | Yes |
| 11188 |  CHEMBL125326 | C18H33N3 | 291.483 | 1 / 0 | 4.0 | Yes |
| 11190 |  BDBM50271870 | C18H34N3+ | 292.491 | 0 / 1 | 3.6 | Yes |
| 11318 |  CHEMBL2021594 | C40H43N3O6 | 661.799 | 8 / 5 | 3.2 | No |
| 11321 |  Norbinaltorphimine | C40H43N3O6 | 661.799 | 8 / 5 | 3.2 | No |
| 11350 |  CHEMBL93614 | C22H29NO2 | 339.479 | 3 / 2 | 4.5 | Yes |
| 11550 |  CHEMBL442709 | C21H21NO2S | 351.464 | 4 / 1 | 2.4 | Yes |
| 11613 |  BDBM50098673 | C25H24N2O3 | 400.478 | 4 / 3 | 3.7 | Yes |
| 11616 |  CHEMBL611697 | C25H24N2O3 | 400.478 | 4 / 3 | 3.7 | Yes |
| 11670 |  CHEMBL272050 | C20H25N3O2 | 339.439 | 4 / 0 | 3.7 | Yes |
| 11941 |  CHEMBL97246 | C22H25N3OS | 379.522 | 4 / 0 | 4.8 | Yes |
| 11980 |  CHEMBL346165 | C27H27N3O3 | 441.531 | 5 / 2 | 2.9 | Yes |
| 12086 |  CHEMBL1089542 | C25H35N5O | 421.589 | 3 / 2 | 2.7 | Yes |
| 12137 |  CHEMBL607277 | C13H24N2O | 224.348 | 2 / 0 | 1.6 | Yes |
| 12191 |  CHEMBL415795 | C64H106N22O12 | 1375.69 | 17 / 19 | -2.4 | No |
| 12195 |  CHEMBL262963 | C64H106N22O12 | 1375.69 | 17 / 19 | -2.4 | No |
| 464400 |  CHEMBL3580743 | C37H43F2N7O7 | 735.79 | 10 / 8 | 1.6 | No |
| 13261 |  CHEMBL1834903 | C42H49N3O8 | 723.867 | 11 / 5 | 2.3 | No |
| 13265 |  CHEMBL1834902 | C42H49N3O8 | 723.867 | 11 / 5 | 2.3 | No |
| 13430 |  CHEMBL345208 | C28H30N2O4S | 490.618 | 7 / 2 | 3.1 | Yes |
| 13569 |  CHEMBL1834898 | C46H55N3O9 | 793.958 | 12 / 4 | 4.3 | No |
| 13602 |  CHEMBL3264748 | C31H34N2O5 | 514.622 | 6 / 1 | 3.9 | No |
| 521856 |  CHEMBL3823054 | C33H51N9O5 | 653.829 | 8 / 9 | 0.4 | No |
| 14000 |  CHEMBL263366 | C71H113N19O16 | 1488.8 | 20 / 19 | -2.8 | No |
| 14214 |  CHEMBL264733 | C65H106N20O14 | 1391.69 | 19 / 19 | -4.6 | No |
| 14219 |  CHEMBL217049 | C65H106N20O14 | 1391.69 | 19 / 19 | -4.6 | No |
| 14313 |  CHEMBL275025 | C22H24Cl2N2O | 403.347 | 2 / 0 | 4.7 | Yes |
| 464633 |  CHEMBL3582484 | C37H44FN7O7 | 717.799 | 9 / 8 | 1.5 | No |
| 14803 |  CHEMBL3217021 | C29H35Cl2N3O4 | 560.516 | 6 / 6 | N/A | No |
| 15277 |  CHEMBL2372395 | C28H38N6O7S | 602.707 | 9 / 5 | 0.1 | No |
| 15357 |  CHEMBL2147917 | C25H26N2O3 | 402.494 | 5 / 2 | 3.4 | Yes |
| 15370 |  CHEMBL2370626 | C59H93N21O12S2 | 1352.65 | 18 / 18 | -3.5 | No |
| 15374 |  CHEMBL2112652 | C59H93N21O12S2 | 1352.65 | 18 / 18 | -3.5 | No |
| 15376 |  CHEMBL2111843 | C59H93N21O12S2 | 1352.65 | 18 / 18 | -3.5 | No |
| 15380 |  CHEMBL2369128 | C59H93N21O12S2 | 1352.65 | 18 / 18 | -3.5 | No |
| 15508 |  CHEMBL107358 | C15H22Cl2N2O | 317.254 | 2 / 1 | 3.5 | Yes |
| 15565 |  CHEMBL572875 | C26H45N3 | 399.667 | 3 / 1 | 6.5 | No |
| 15632 |  M3A6S | C19H21NO7S | 407.437 | 7 / 1 | -1.8 | Yes |
| 15670 |  CHEMBL127828 | C23H22FN3OS | 407.507 | 5 / 1 | 4.3 | Yes |
| 15799 |  CHEMBL61940 | C22H24N2O3 | 364.445 | 4 / 3 | 2.4 | Yes |
| 15802 |  CHEMBL611129 | C22H24N2O3 | 364.445 | 4 / 3 | 2.4 | Yes |
| 15842 |  CHEMBL134201 | C27H26FNO4 | 447.506 | 6 / 2 | 4.1 | Yes |
| 16162 |  SCHEMBL9815317 | C26H30Cl2N2O7 | 553.433 | 8 / 4 | N/A | No |
| 16289 |  CHEMBL329114 | C22H25F3N2OS | 422.51 | 6 / 0 | 4.4 | Yes |
| 464904 |  CHEMBL3589710 | C26H32N4O | 416.569 | 4 / 2 | 4.6 | Yes |
| 16473 |  CHEMBL1917708 | C16H24ClNO | 281.824 | 2 / 1 | N/A | N/A |
| 16784 |  Pipamperone | C21H30FN3O2 | 375.488 | 5 / 1 | 2.0 | Yes |
| 17227 |  CHEMBL1782985 | C22H29Cl2N3O3 | 454.392 | 4 / 0 | 3.8 | Yes |
| 459368 |  BDBM50140910 | C20H20N2O2 | 320.392 | 4 / 1 | 2.4 | Yes |
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