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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL378753
Molecular formula	C26H27N3O4
IUPAC name	N-[(E)-[(7aS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene]amino]benzamide
Molecular weight	445.519
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	3.5
Synonyms	BDBM50189257
Inchi Key	AKXCFAYOTIEFOH-SOJWNWKASA-N
Inchi ID	InChI=1S/C26H27N3O4/c1-2-13-29-14-12-25-21-17-8-9-19(30)22(21)33-23(25)18(10-11-26(25,32)20(29)15-17)27-28-24(31)16-6-4-3-5-7-16/h2-9,20,23,30,32H,1,10-15H2,(H,28,31)/b27-18+/t20?,23-,25?,26?/m1/s1
PubChem CID	44414890
ChEMBL	CHEMBL378753
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7982	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
7983	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
7984	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
7985	Nociceptin receptor	P47748	OPRL1	Cavia porcellus (Guinea pig)	370

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