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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3580743
Molecular formula	C37H43F2N7O7
IUPAC name	(2S,5S,8S,16R)-16-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-benzyl-5-[(2,4-difluorophenyl)methyl]-3,6,10,17-tetraoxo-1,4,7,11-tetrazacycloheptadecane-8-carboxamide
Molecular weight	735.79
Hydrogen bond acceptor	10
Hydrogen bond donor	8
XlogP	1.6
Synonyms	BDBM50092198
Inchi Key	ARPMOQQOTWEYPJ-JZVHMONDSA-N
Inchi ID	InChI=1S/C37H43F2N7O7/c38-24-12-11-23(26(39)19-24)18-31-37(53)44-29(33(41)49)20-32(48)42-15-5-4-8-28(43-34(50)27(40)16-22-9-13-25(47)14-10-22)35(51)45-30(36(52)46-31)17-21-6-2-1-3-7-21/h1-3,6-7,9-14,19,27-31,47H,4-5,8,15-18,20,40H2,(H2,41,49)(H,42,48)(H,43,50)(H,44,53)(H,45,51)(H,46,52)/t27-,28+,29-,30-,31-/m0/s1
PubChem CID	122178420
ChEMBL	CHEMBL3580743
IUPHAR	N/A
BindingDB	50092198
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
464398	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
464401	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
464397	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
464400	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
464399	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
464402	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398

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