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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL611129
Molecular formula	C22H24N2O3
IUPAC name	(1S,2S,9R,17R)-18-(cyclopropylmethyl)-10-oxa-7,18-diazahexacyclo[9.9.1.01,9.02,17.04,8.015,21]henicosa-4(8),5,11,13,15(21)-pentaene-2,12-diol
Molecular weight	364.445
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	2.4
Synonyms	6,7-(1-Aza-2-propene-1,3-diyl)-4,5alpha-epoxy-17-(cyclopropylmethyl)-6,7-didehydromorphinan-3,14-diol
Inchi Key	AVZPNFQSUXLGJJ-YPVJZLTNSA-N
Inchi ID	InChI=1S/C22H24N2O3/c25-15-4-3-13-9-16-22(26)10-14-5-7-23-18(14)20-21(22,17(13)19(15)27-20)6-8-24(16)11-12-1-2-12/h3-5,7,12,16,20,23,25-26H,1-2,6,8-11H2/t16-,20+,21+,22-/m1/s1
PubChem CID	46877686
ChEMBL	CHEMBL611129
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15801	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
15802	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
15803	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98

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