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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Kappa-type opioid receptor
Species	Cavia porcellus (Guinea pig)
Gene	OPRK1
Synonym	K-OR-1 KOR-1
Disease	N/A for non-human GPCRs
Length	380
Amino acid sequence	MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
UniProt	P41144
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3952
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3298899
Molecular formula	C24H29N3O4
IUPAC name	(4aR,8S,8aR)-4-[(4-methoxyphenyl)methyl]-8-[(4-methoxyphenyl)methylamino]-4a,5,6,7,8,8a-hexahydro-1H-quinoxaline-2,3-dione
Molecular weight	423.513
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.8
Synonyms	BDBM50021995
Inchi Key	AMNQEEATZWWARG-BHDDXSALSA-N
Inchi ID	InChI=1S/C24H29N3O4/c1-30-18-10-6-16(7-11-18)14-25-20-4-3-5-21-22(20)26-23(28)24(29)27(21)15-17-8-12-19(31-2)13-9-17/h6-13,20-22,25H,3-5,14-15H2,1-2H3,(H,26,28)/t20-,21+,22+/m0/s1
PubChem CID	90645387
ChEMBL	CHEMBL3298899
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	5.0 %	PMID24856182	ChEMBL

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