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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL307235
Molecular formula	C23H28Cl2N2O3
IUPAC name	2-(3,4-dichlorophenyl)-N-methyl-N-[(5S,7S,8S)-3-methylidene-2-oxo-8-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-7-yl]acetamide
Molecular weight	451.388
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.5
Synonyms	2-(3,4-Dichloro-phenyl)-N-methyl-N-(3-methylene-2-oxo-8-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-7-yl)-acetamide(SMBU-1) BDBM50000786 2-(3,4-Dichlorophenyl)-N-methyl-N-[(5S)-3-methylene-2-oxo-8beta-(1-pyrrolidinyl)-1-oxaspiro[4.5]decan-7alpha-yl]acetamide
Inchi Key	AIGXNGMYDUNNBN-JTAQYXEDSA-N
Inchi ID	InChI=1S/C23H28Cl2N2O3/c1-15-13-23(30-22(15)29)8-7-19(27-9-3-4-10-27)20(14-23)26(2)21(28)12-16-5-6-17(24)18(25)11-16/h5-6,11,19-20H,1,3-4,7-10,12-14H2,2H3/t19-,20-,23-/m0/s1
PubChem CID	15177773
ChEMBL	CHEMBL307235
IUPHAR	N/A
BindingDB	50000786
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6200	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
6199	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
6198	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98

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