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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3759541
Molecular formula	C35H36N4O4
IUPAC name	(3R)-2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-N-[2-oxo-2-(N-phenylanilino)ethyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Molecular weight	576.697
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.7
Synonyms	BDBM50142703
Inchi Key	AAUPKJITIZNIAU-AJQTZOPKSA-N
Inchi ID	InChI=1S/C35H36N4O4/c1-23-17-29(40)18-24(2)30(23)20-31(36)35(43)38-22-26-12-10-9-11-25(26)19-32(38)34(42)37-21-33(41)39(27-13-5-3-6-14-27)28-15-7-4-8-16-28/h3-18,31-32,40H,19-22,36H2,1-2H3,(H,37,42)/t31-,32+/m0/s1
PubChem CID	127029282
ChEMBL	CHEMBL3759541
IUPHAR	N/A
BindingDB	50142703
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521450	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
521451	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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