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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL382597
Molecular formula	C36H45N3O3
IUPAC name	3-(5-hydroxy-3,4-dihydro-1H-isoquinolin-2-yl)-N-[(7R)-5-(3-hydroxyphenyl)-4-methyl-2-(3-phenylpropyl)-2-azabicyclo[3.3.1]nonan-7-yl]propanamide
Molecular weight	567.774
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	6.0
Synonyms	N/A
Inchi Key	AJHLWUQDIIXEEO-MNJVNLEGSA-N
Inchi ID	InChI=1S/C36H45N3O3/c1-26-24-39(17-7-10-27-8-3-2-4-9-27)31-21-30(22-36(26,23-31)29-12-6-13-32(40)20-29)37-35(42)16-19-38-18-15-33-28(25-38)11-5-14-34(33)41/h2-6,8-9,11-14,20,26,30-31,40-41H,7,10,15-19,21-25H2,1H3,(H,37,42)/t26?,30-,31?,36?/m0/s1
PubChem CID	44408410
ChEMBL	CHEMBL382597
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6921	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
6920	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
6922	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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