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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL365483
Molecular formula	C22H27NO
IUPAC name	8,8-dimethyl-7-[methyl-[(E)-3-phenylprop-2-enyl]amino]-6,7-dihydro-5H-naphthalen-2-ol
Molecular weight	321.464
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.3
Synonyms	BDBM50154209 8,8-Dimethyl-7-[methyl-((E)-3-phenyl-allyl)-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol
Inchi Key	AHIRZFCBGSMDPL-JXMROGBWSA-N
Inchi ID	InChI=1S/C22H27NO/c1-22(2)20-16-19(24)13-11-18(20)12-14-21(22)23(3)15-7-10-17-8-5-4-6-9-17/h4-11,13,16,21,24H,12,14-15H2,1-3H3/b10-7+
PubChem CID	11198030
ChEMBL	CHEMBL365483
IUPHAR	N/A
BindingDB	50154209
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5581	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
5580	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
5582	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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