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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB-0304
Molecular formula	C25H29N5O5
IUPAC name	(2R)-2-[(4S)-4-amino-8-hydroxy-3-oxo-4,5-dihydro-1H-2-benzazepin-2-yl]-N-[(4S)-2-(2-amino-2-oxoethyl)-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]propanamide
Molecular weight	479.537
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-0.2
Synonyms	BDBM50376593 D08LIT CHEMBL409225
Inchi Key	ACFTTXWQZSBVGL-OREJSRFESA-N
Inchi ID	InChI=1S/C25H29N5O5/c1-14(30-12-18-8-19(31)7-6-16(18)9-20(26)24(30)34)23(33)28-21-10-15-4-2-3-5-17(15)11-29(25(21)35)13-22(27)32/h2-8,14,20-21,31H,9-13,26H2,1H3,(H2,27,32)(H,28,33)/t14-,20+,21+/m1/s1
PubChem CID	11641503
ChEMBL	CHEMBL409225
IUPHAR	N/A
BindingDB	50376593
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1529	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
1531	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
1534	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
1533	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
1528	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
1530	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
1532	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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